Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.65 |
| ▸ | RAB9A | P51151 | 4/20 | 0.62 |
| ▸ | GAA | P10253 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | CD274 | Q9NZQ7 | 4/20 | 0.56 |
| ▸ | BCHE | P06276 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | NPY1R | P25929 | 1/20 | 0.53 |
| ▸ | NPY2R | P49146 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3458474 | 0.89 | KMT2A (0.70) | HTTRAB9AGAAALDH1A1MAPT | |
| SCHEMBL5113589 | 0.89 | BCHE (0.69) | HTTRAB9AALDH1A1BCHEKMT2A | |
| SCHEMBL3458568 | 0.84 | HTT (0.64) | HTTRAB9AGAAALDH1A1MAPT | |
| SCHEMBL5113660 | 0.82 | BCHE (0.57) | HTTRAB9AGAAALDH1A1MAPT | |
| SCHEMBL5315461 | 0.82 | BCHE (0.67) | HTTRAB9AALDH1A1BCHEKMT2A | |
| SCHEMBL3458730 | 0.82 | KMT2A (0.55) | HTTRAB9AGAAMAPTCD274 | |
| SCHEMBL5098443 | 0.81 | KMT2A (0.70) | HTTRAB9AGAAALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL4949263 | 0.77 | BCHE (0.77) | HTTRAB9AALDH1A1BCHEKMT2A | |
| SCHEMBL3411267 | 0.77 | RAB9A (0.60) | HTTRAB9AGAAALDH1A1MAPT | |
| SCHEMBL14078198 | 0.77 | KMT2A (0.64) | HTTRAB9AGAAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010010435-A2 | FUSED OXAZOLE AND THIAZOLE DERIVATIVES AS TRPMS MODULATORS | GLENMARK PHARMACEUTICAL S.A. (CH) | 2010-01-28 | — | — | WO | disclosed |