Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 1/20 | 0.51 |
| ▸ | GABRD | O14764 | 1/20 | 0.51 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.51 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.51 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.51 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.51 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.51 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.51 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.51 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.51 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.51 |
| ▸ | GABRE | P78334 | 1/20 | 0.51 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.51 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.51 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.51 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.51 |
| ▸ | KDM4C | Q9H3R0 | 8/20 | 0.49 |
| ▸ | KDM5C | P41229 | 6/20 | 0.49 |
| ▸ | KDM2A | Q9Y2K7 | 5/20 | 0.49 |
| ▸ | KDM3A | Q9Y4C1 | 5/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17545205 | 0.81 | GABRP (0.56) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL23583774 | 0.77 | KDM4C (0.57) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL1244717 | 0.76 | GABRP (0.44) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL29453118 | 0.75 | KDM4C (0.55) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL1759894 | 0.75 | KDM4C (0.55) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7704763 | 0.75 | KDM4C (0.55) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL25933765 | 0.74 | KDM4C (0.53) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL25937937 | 0.73 | KDM4C (0.49) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL31133240 | 0.73 | KDM4C (0.49) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL28976353 | 0.72 | KDM4C (0.52) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2231662-A1 | 8-ANILIN0IMIDAZ0PYRIDINES AND THEIR USE AS ANTI-CANCER AND/OR ANTI-INFLAMMATORY AGENTS | Genentech, Inc. (US) | 2010-09-29 | — | — | EP | disclosed |
| WO-2009085980-A1 | 8-ANILIN0IMIDAZ0PYRIDINES AND THEIR USE AS ANTI-CANCER AND/OR ANTI-INFLAMMATORY AGENTS | GENENTECH, INC. (US) | 2009-07-09 | — | — | WO | disclosed |