Methacrylic Acid

Methacrylic Acid

SCHEMBL3458994

C=C(C)C(=O)O.C=CC1CC1

nearest known ligand 0.33

Full drug profile on Sugi Atlas →

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
TDP1 Q9NUW8 1/20 0.32
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL28186426 0.89 GRIK1 (0.35) ALDH1A1
Acetic Acid SCHEMBL31249677 0.87
Bicarbonate SCHEMBL9715828 0.82
SCHEMBL12366317 0.76 KMT2A (0.39) ALDH1A1KMT2A
Methyl Alcohol SCHEMBL8053975 0.76 ALDH1A1 (0.38) ALDH1A1
Methacrylic Acid SCHEMBL3288565 0.74 TDP1 (0.38) ALDH1A1TDP1
Methacrylic Acid SCHEMBL18109770 0.73 ALDH1A1 (0.44) ALDH1A1TDP1
Methacrylic Acid SCHEMBL539234 0.73
Methacrylic Acid SCHEMBL29610 0.73 ALDH1A1 (0.44) ALDH1A1TDP1
Methacrylic Acid SCHEMBL4171527 0.73 ALDH1A1 (0.44) ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3278786-B1 DENTAL MATERIALS ON THE BASIS OF VINYLCYCLOPROPANE DERIVATIVES CONTAINING URETHANE GROUPS IVOCLAR VIVADENT AG (LI) 2019-01-23 EP disclosed
EP-3278786-A1 DENTAL MATERIALS ON THE BASIS OF VINYLCYCLOPROPANE DERIVATIVES CONTAINING URETHANE GROUPS Ivoclar Vivadent AG (LI) 2018-02-07 EP disclosed
US-7816476-B2 Polymerizable cyclopropyl acrylates IVOCLAR VIVADENT AG (LI) 2010-10-19 US disclosed
EP-1413569-B1 Bicyclic cyclopropane derivatives capable of polymerisation and their use in the preparation of dental materials IVOCLAR VIVADENT AG (LI) 2006-12-13 EP disclosed
US-20060178469-A1 Polymerizable cyclopropyl acrylates IVOCLAR VIVADENT AG 2006-08-10 US disclosed
EP-1413569-A1 Bicyclic cyclopropane derivatives capable of polymerisation and their use in the preparation of dental materials Ivoclar Vivadent AG (LI) 2004-04-28 EP disclosed
EP-0943601-B1 Vinylcyclopropane-(meth)acrylates as well as their use IVOCLAR VIVADENT AG (LI) 2003-05-02 EP disclosed
EP-0943601-B1 Vinylcyclopropane-(meth)acrylates as well as their use IVOCLAR VIVADENT AG (LI) 2003-05-02 EP disclosed
US-6136887-A Vinylcyclopropane-(meth)acrylates and their use IVOCLAR AG (LI) 2000-10-24 US disclosed
US-6136887-A Vinylcyclopropane-(meth)acrylates and their use IVOCLAR AG (LI) 2000-10-24 US disclosed
EP-0943601-A1 Vinylcyclopropane-(meth)acrylates as well as their use IVOCLAR AG (LI) 1999-09-22 EP disclosed
EP-0943601-A1 Vinylcyclopropane-(meth)acrylates as well as their use IVOCLAR AG (LI) 1999-09-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060178469-A1 Polymerizable cyclopropyl acrylates CBR3, CBR1, ACAD9 ALDH1A1 2762/4885TDP1 4095/4885KMT2A 2615/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.