Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
| ▸ | LIPC | P11150 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | LIPE | Q05469 | 1/20 | 0.50 |
| ▸ | ELANE | P08246 | 2/20 | 0.49 |
| ▸ | MGLL | Q99685 | 3/20 | 0.41 |
| ▸ | FAAH | O00519 | 3/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | GABRP | O00591 | 2/20 | 0.38 |
| ▸ | GABRD | O14764 | 2/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.38 |
| ▸ | GABRE | P78334 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3458598 | 0.81 | MGLL (0.49) | MGLLFAAHGABRPGABRDGABRA1 | |
| SCHEMBL3458691 | 0.76 | BCHE (0.48) | BCHELIPCACHELIPEELANE | |
| SCHEMBL3458662 | 0.74 | BCHE (0.54) | BCHELIPCACHELIPEELANE | |
| SCHEMBL3458193 | 0.73 | BCHE (0.50) | BCHELIPCACHELIPEELANE | |
| SCHEMBL2853749 | 0.71 | BCHE (0.68) | BCHELIPCACHELIPEELANE | |
| SCHEMBL7044271 | 0.69 | BCHE (0.56) | BCHELIPCACHELIPEMGLL | |
| SCHEMBL6552559 | 0.67 | BCHE (1.00) | BCHELIPCACHELIPEMGLL | |
| SCHEMBL10662155 | 0.66 | ELANE (1.00) | ELANEMEN1KMT2A | |
| SCHEMBL7044238 | 0.65 | BCHE (0.81) | BCHELIPCACHELIPEMGLL | |
| SCHEMBL5492954 | 0.65 | ELANE (0.45) | BCHEACHEELANEMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010151160-A1 | O-SUBSTITUTED 3-N-HETEROARYL-1,3,4-OXADIAZOLONES FOR MEDICAL USE | BIAL - PORTELA & CA., S.A. (PT) | 2010-12-29 | — | — | WO | claimed |
| WO-2010151160-A1 | O-SUBSTITUTED 3-N-HETEROARYL-1,3,4-OXADIAZOLONES FOR MEDICAL USE | BIAL - PORTELA & CA., S.A. (PT) | 2010-12-29 | — | — | WO | disclosed |