Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.54 |
| ▸ | LIPC | P11150 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | LIPE | Q05469 | 1/20 | 0.54 |
| ▸ | MGLL | Q99685 | 4/20 | 0.44 |
| ▸ | FAAH | O00519 | 3/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KDM5A | P29375 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3458193 | 0.80 | BCHE (0.50) | BCHELIPCACHELIPEMGLL | |
| SCHEMBL14446902 | 0.75 | SMN1; SMN2 (0.50) | MAPTRAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL3459053 | 0.74 | BCHE (0.50) | BCHELIPCACHELIPEMGLL | |
| SCHEMBL2853749 | 0.74 | BCHE (0.68) | BCHELIPCACHELIPEMGLL | |
| SCHEMBL3458691 | 0.73 | BCHE (0.48) | BCHELIPCACHELIPEMGLL | |
| SCHEMBL7044271 | 0.73 | BCHE (0.56) | BCHELIPCACHELIPEMGLL | |
| SCHEMBL15778047 | 0.73 | KDM5A (0.64) | HTTNPC1MAPTRAB9AKDM5A | |
| SCHEMBL25407433 | 0.69 | ALDH1A1 (0.43) | HTTNPC1MAPTRAB9AKDM5A | |
| SCHEMBL7044238 | 0.69 | BCHE (0.81) | BCHELIPCACHELIPEMGLL | |
| SCHEMBL2233786 | 0.67 | MGLL (0.76) | BCHELIPCACHELIPEMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010151160-A1 | O-SUBSTITUTED 3-N-HETEROARYL-1,3,4-OXADIAZOLONES FOR MEDICAL USE | BIAL - PORTELA & CA., S.A. (PT) | 2010-12-29 | — | — | WO | claimed |
| WO-2010151160-A1 | O-SUBSTITUTED 3-N-HETEROARYL-1,3,4-OXADIAZOLONES FOR MEDICAL USE | BIAL - PORTELA & CA., S.A. (PT) | 2010-12-29 | — | — | WO | disclosed |