Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.49 |
| ▸ | DGKA | P23743 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | P2RY10 | O00398 | 5/20 | 0.44 |
| ▸ | GPR34 | Q9UPC5 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL345914 | 1.00 | NOD1 (0.49) | NOD1DGKAHTR2CNAAAP2RY10 | |
| SCHEMBL1443698 | 1.00 | NOD1 (0.49) | NOD1DGKAHTR2CNAAAP2RY10 | |
| Hydrochloric Acid SCHEMBL8725903 | 0.98 | NOD1 (0.48) | NOD1DGKAHTR2CNAAAP2RY10 | |
| Hydrochloric Acid SCHEMBL14719876 | 0.98 | NOD1 (0.48) | NOD1DGKAHTR2CNAAAP2RY10 | |
| SCHEMBL2452768 | 0.95 | NOD1 (0.54) | NOD1DGKAHTR2CNAAAP2RY10 | |
| SCHEMBL30556 | 0.95 | NOD1 (0.54) | NOD1DGKAHTR2CNAAAP2RY10 | |
| SCHEMBL30558 | 0.95 | NOD1 (0.54) | NOD1DGKAHTR2CNAAAP2RY10 | |
| SCHEMBL10535639 | 0.93 | HTR2C (0.57) | NOD1DGKAHTR2CNAAAP2RY10 | |
| SCHEMBL11966748 | 0.93 | HTR2C (0.57) | NOD1DGKAHTR2CNAAAP2RY10 | |
| SCHEMBL4947876 | 0.93 | HTR2C (0.57) | NOD1DGKAHTR2CNAAAP2RY10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3684416-A1 | PSMA-TARGETING AMANITIN CONJUGATES | Heidelberg Pharma Research GmbH (DE) | 2020-07-29 | — | — | EP | disclosed |
| WO-2019057964-A1 | PSMA-TARGETING AMANITIN CONJUGATES | HEIDELBERG PHARMA RESEARCH GMBH (DE) | 2019-03-28 | — | — | WO | disclosed |
| US-9458188-B2 | Efficient peptide couplings and their use in the synthesis and isolation of a cyclopenta (G) quinazoline trisodium salt | BTG INTERNATIONAL LIMITED (GB) | 2016-10-04 | — | — | US | disclosed |
| US-9107931-B2 | Class of cationic lipids for transporting active agents into cells | OZ BIOSCIENCES (FR) | 2015-08-18 | — | — | US | disclosed |
| WO-2012087888-A2 | EFFICIENT PEPTIDE COUPLINGS AND THEIR USE IN THE SYNTHESIS AND ISOLATION OF A CYCLOPENTA (G) QUINAZOLINE TRISODIUM SALT | ONYX PHARMACEUTICALS, INC. (US) | 2012-06-28 | — | — | WO | disclosed |
| US-20120015865-A1 | NOVEL CLASS OF CATIONIC LIPIDS FOR TRANSPORTING ACTIVE AGENTS INTO CELLS | OZ BIOSCIENCES (FR) | 2012-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120015865-A1 | NOVEL CLASS OF CATIONIC LIPIDS FOR TRANSPORTING ACTIVE AGENTS INTO CELLS | SLC7A1, SLC75A1, SLC47A2 | NOD1 3592/4885DGKA 1131/4885HTR2C 4836/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.