Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.35 |
| ▸ | ERCC5 | P28715 | 2/20 | 0.35 |
| ▸ | FEN1 | P39748 | 2/20 | 0.35 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CTBP2 | P56545 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5998860 | 1.00 | FOLH1 (0.37) | FOLH1ALDH1A1ALOX15AKR1C1ERCC5 | |
| SCHEMBL3459377 | 0.83 | CA12 (0.36) | FOLH1ALDH1A1L3MBTL1HIF1ATSHR | |
| SCHEMBL5998857 | 0.83 | CA12 (0.36) | FOLH1ALDH1A1L3MBTL1HIF1ATSHR | |
| SCHEMBL5998853 | 0.83 | CA12 (0.36) | FOLH1ALDH1A1L3MBTL1HIF1ATSHR | |
| SCHEMBL3459412 | 0.82 | FOLH1 (0.37) | FOLH1ALDH1A1ALOX15AKR1C1ERCC5 | |
| SCHEMBL7459530 | 0.82 | FOLH1 (0.37) | FOLH1ALDH1A1ALOX15AKR1C1ERCC5 | |
| SCHEMBL5997915 | 0.81 | HPGD (0.41) | ALDH1A1L3MBTL1HIF1ATSHRLMNA | |
| SCHEMBL5997805 | 0.81 | TSHR (0.38) | ALDH1A1CLCN2L3MBTL1TSHRHTT | |
| SCHEMBL9021457 | 0.79 | HDAC3 (0.40) | ALDH1A1HIF1ATSHRHTTTP53 | |
| SCHEMBL9021460 | 0.79 | HDAC3 (0.40) | ALDH1A1HIF1ATSHRHTTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1683792-B9 | BENZOPYRONE COMPOUNDS, PREPARATION METHOD AND USE THEREOF | SHENYANG SINOCHEM AGROCHEMICALS R & D CO LTD (CN) | 2016-10-05 | — | — | EP | disclosed |
| EP-1683792-B1 | BENZOPYRONE COMPOUNDS, PREPARATION METHOD AND USE THEREOF | SHENYANG SINOCHEM AGROCHEMICALS R & D CO LTD (CN) | 2016-07-20 | — | — | EP | disclosed |
| US-7642364-B2 | Benzopyrone compounds, preparation method and use thereof | SHENYANG RESEARCH INSTITUTE OF CHEMICAL INDUSTRY (CN) | 2010-01-05 | — | — | US | disclosed |
| US-20070037876-A1 | good insecticide activity against armyworm, diamond backmoth, aphids, carmine spider mite, two-spotted spider mite, lady beetles, mites and culex mosquitoes, especially for lady beetles and culex mosquitoes; wide spectrum fungicidal activity | SHENYANG SINOCHEM AGROCHEMICALS R&D CO., LTD. (CN) | 2007-02-15 | — | — | US | disclosed |
| EP-1683792-A1 | BENZOPYRONE COMPOUNDS, PREPARATION METHOD AND USE THEREOF | Shenyang Research Institute of Chemical Industry (CN) | 2006-07-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070037876-A1 | good insecticide activity against armyworm, diamond backmoth, aphids, carmine spider mite, two-spotted spider mite, lady beetles, mites and culex mosquitoes, especially for lady beetles and culex mosquitoes; wide spectrum fungicidal activity | DDT, BROX, LRRK2 | FOLH1 3874/4885ALDH1A1 2701/4885ALOX15 2430/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.