Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.35 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3459412 | 1.00 | FOLH1 (0.37) | FOLH1AKR1C3ALDH1A1LMNAALOX15 | |
| SCHEMBL7691194 | 0.85 | ERCC5 (0.36) | FOLH1AKR1C3ALDH1A1LMNAALOX15 | |
| SCHEMBL7691197 | 0.84 | FOLH1 (0.36) | FOLH1ALDH1A1LMNAALOX15CLCN2 | |
| SCHEMBL7459526 | 0.83 | ALDH1A1 (0.39) | FOLH1ALDH1A1LMNATSHR | |
| SCHEMBL5080478 | 0.83 | ALDH1A1 (0.39) | FOLH1ALDH1A1LMNATSHR | |
| SCHEMBL3459410 | 0.83 | ALDH1A1 (0.39) | FOLH1ALDH1A1LMNATSHR | |
| SCHEMBL3459380 | 0.82 | FOLH1 (0.37) | FOLH1ALDH1A1LMNAALOX15AKR1C1 | |
| SCHEMBL5998860 | 0.82 | FOLH1 (0.37) | FOLH1ALDH1A1LMNAALOX15AKR1C1 | |
| SCHEMBL5669568 | 0.81 | ALDH1A1 (0.43) | ALDH1A1LMNATSHRHTT | |
| SCHEMBL7684484 | 0.81 | LMNA (0.33) | FOLH1ALDH1A1LMNAPTPN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2565180-A2 | ALPHA-ARYLMETHOXYACRYLATE DERIVATIVE, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | Oscotec Inc. (KR) | 2013-03-06 | — | — | EP | disclosed |
| EP-0811614-B1 | Benzyloxy substituted aromatics and their use as fungicides and insecticides | DOW AGROSCIENCES LLC (US) | 2002-09-25 | — | — | EP | disclosed |
| EP-1070052-A1 | FUNGICIDE COMPOSITIONS COMPRISING A HYDROXIMIC OR HYDRAZONIC GROUP | AVENTIS CROPSCIENCE S.A. (FR) | 2001-01-24 | — | — | EP | disclosed |
| EP-1021399-A2 | FUNGICIDES WITH HYDROXIMIC AND HYDRAZONIC GROUPS | AVENTIS CROPSCIENCE S.A. (FR) | 2000-07-26 | — | — | EP | disclosed |
| US-6043282-A | FUNGICIDES, PESTICIDES, INSECTICIDES, NEMATOCIDES, MITICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2000-03-28 | — | — | US | disclosed |
| WO-1999051579-A1 | FUNGICIDE COMPOSITIONS COMPRISING A HYDROXIMIC OR HYDRAZONIC GROUP | AVENTIS CROPSCIENCE S.A. (FR) | 1999-10-14 | — | — | WO | disclosed |
| US-5886015-A | APPLYING FUNGICIDE OR INSECTICIDE TO THE LOCUS OF THE SEED, PLANT OR SOIL | ROHM AND HAAS COMPANY (US) | 1999-03-23 | — | — | US | disclosed |
| WO-1998015512-A2 | FUNGICIDES WITH HYDROXIMIC AND HYDRAZONIC GROUPS | RHONE POULENC AGROCHIMIE (FR) | 1998-04-16 | — | — | WO | disclosed |
| EP-0811614-A1 | Benzyloxy substituted aromatics and their use as fungicides and insecticides | ROHM AND HAAS COMPANY (US) | 1997-12-10 | — | — | EP | disclosed |
| US-5371268-A | Ortho-substituted benzyl esters of cyclopropanecarboxylic acids | BASF AKTIENGESELLSCHAFT (DE) | 1994-12-06 | — | — | US | disclosed |
| EP-0532022-A1 | Acrylate compound, preparation process thereof and fungicide using the same | UBE INDUSTRIES, LTD. (JP) | 1993-03-17 | — | — | EP | disclosed |
| US-4822908-A | Substituted acrylates and fungicides containing same | BASF AKTIENGESELLSCHAFT (DE) | 1989-04-18 | — | — | US | disclosed |