Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AIMP2 | Q13155 | 1/20 | 0.50 |
| ▸ | SRC | P12931 | 5/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.46 |
| ▸ | EGFR | P00533 | 4/20 | 0.44 |
| ▸ | INSR | P06213 | 1/20 | 0.44 |
| ▸ | IGF1R | P08069 | 1/20 | 0.44 |
| ▸ | MET | P08581 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | TEK | Q02763 | 1/20 | 0.44 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.43 |
| ▸ | ITK | Q08881 | 1/20 | 0.43 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | BCR | P11274 | 1/20 | 0.43 |
| ▸ | PRKCA | P17252 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | PRKACA | P17612 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3458886 | 0.88 | EPHX2 (0.51) | AIMP2SRCPDGFRBEPHX2EGFR | |
| SCHEMBL3458766 | 0.85 | AIMP2 (0.58) | AIMP2SRCPDGFRBEGFRINSR | |
| SCHEMBL13924567 | 0.83 | SYK (0.62) | AIMP2SRCEGFRCDK2PRKCD | |
| SCHEMBL4878754 | 0.82 | AIMP2 (0.54) | AIMP2SRCPDGFRBEPHX2EGFR | |
| SCHEMBL3459161 | 0.82 | SRC (0.57) | AIMP2SRCEPHX2EGFRITK | |
| SCHEMBL3454379 | 0.79 | AIMP2 (0.56) | AIMP2SRCPDGFRBEPHX2EGFR | |
| SCHEMBL14024413 | 0.78 | EGFR (0.50) | AIMP2SRCPDGFRBEGFRINSR | |
| SCHEMBL3455091 | 0.77 | SYK (0.61) | EGFRSCN5ASCN9APRKCDROCK2 | |
| SCHEMBL14024524 | 0.77 | KDR (0.54) | AIMP2SRCPDGFRBEPHX2EGFR | |
| SCHEMBL19476605 | 0.76 | IGF1R (0.58) | AIMP2SRCPDGFRBEGFRINSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2154967-A1 | PYRIMIDINE DERIVATIVES | Hutchison Medipharma Enterprises Limited (BS) | 2010-02-24 | — | — | EP | disclosed |
| WO-2008128231-A1 | PYRIMIDINE DERIVATIVES | HUTCHISON MEDIPHARMA ENTERPRISES LIMITED (BS) | 2008-10-23 | — | — | WO | disclosed |