Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.72 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.67 |
| ▸ | PARP1 | P09874 | 6/20 | 0.62 |
| ▸ | PARP10 | Q53GL7 | 5/20 | 0.62 |
| ▸ | PARP15 | Q460N3 | 4/20 | 0.62 |
| ▸ | PARP14 | Q460N5 | 2/20 | 0.62 |
| ▸ | CSF1R | P07333 | 1/20 | 0.61 |
| ▸ | FLT1 | P17948 | 1/20 | 0.61 |
| ▸ | FLT3 | P36888 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.61 |
| ▸ | CDK9 | P50750 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.61 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4004339 | 0.86 | KCNK3 (0.76) | MEN1KMT2ASIRT1PARP1PARP10 | |
| SCHEMBL6821211 | 0.85 | HPSE (0.78) | MEN1KMT2ASIRT1TP53EPHX1 | |
| SCHEMBL4893340 | 0.85 | PARP1 (0.66) | MEN1KMT2APARP1PARP10PARP15 | |
| SCHEMBL14289778 | 0.84 | PARP1 (0.68) | MEN1KMT2APARP1PARP10PARP15 | |
| SCHEMBL4918597 | 0.84 | KMT2A (1.00) | MEN1KMT2ASIRT1TP53EPHX1 | |
| SCHEMBL2850002 | 0.83 | MEN1 (0.67) | MEN1KMT2APARP1PARP10PARP15 | |
| SCHEMBL3460982 | 0.83 | SMN1; SMN2 (0.68) | KMT2ASIRT1PARP1TP53EPHX1 | |
| SCHEMBL4667222 | 0.83 | MEN1 (0.61) | MEN1KMT2APARP1PARP10PARP15 | |
| SCHEMBL17193484 | 0.82 | TP53 (0.81) | MEN1KMT2ASIRT1TP53EPHX1 | |
| SCHEMBL3069463 | 0.82 | PLAU (0.76) | MEN1KMT2ASIRT1PARP1PARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120196884-A1 | UREA SUBSTITUTED SULPHONAMIDE DERIVATIVES | BIOTIE THERAPIES CORPORATION (FI) | 2012-08-02 | — | — | US | disclosed |
| WO-2010146236-A1 | UREA SUBSTITUTED SULPHONAMIDE DERIVATIVES | BIOTIE THERAPIES CORP. (FI) | 2010-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120196884-A1 | UREA SUBSTITUTED SULPHONAMIDE DERIVATIVES | ITGA1, ITGB1, ITGA2B | MEN1 4730/4885KMT2A 2144/4885SIRT1 989/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.