Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 2/20 | 0.78 |
| ▸ | F2 | P00734 | 1/20 | 0.65 |
| ▸ | PLG | P00747 | 1/20 | 0.65 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.65 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.65 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.65 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | MLYCD | O95822 | 1/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | MMP2 | P08253 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25123079 | 0.87 | SMN1; SMN2 (0.76) | MMP13SMN1; SMN2ALDH1A1MLYCDHDAC6 | |
| SCHEMBL8395225 | 0.87 | SMN1; SMN2 (0.76) | MMP13SMN1; SMN2ALDH1A1MLYCDHDAC6 | |
| SCHEMBL4522241 | 0.87 | SMN1; SMN2 (0.76) | MMP13SMN1; SMN2ALDH1A1MLYCDHDAC6 | |
| SCHEMBL8391563 | 0.85 | SMN1; SMN2 (0.73) | MMP13SMN1; SMN2MLYCDHDAC6CA2 | |
| SCHEMBL10722498 | 0.85 | HDAC6 (0.77) | MMP13F2PLGPRSS1PRSS2 | |
| SCHEMBL8167653 | 0.84 | HDAC6 (0.69) | MMP13SMN1; SMN2ALDH1A1MLYCDHDAC6 | |
| Methyl Alcohol SCHEMBL11518093 | 0.84 | SMN1; SMN2 (0.72) | MMP13SMN1; SMN2MLYCDHDAC6CA2 | |
| SCHEMBL9267844 | 0.83 | ALDH1A1 (0.61) | MMP13F2PLGPRSS1PRSS2 | |
| SCHEMBL8393362 | 0.82 | SMN1; SMN2 (0.68) | MMP13SMN1; SMN2MLYCDHDAC6CA2 | |
| SCHEMBL5967848 | 0.81 | NPC1 (0.57) | MMP13SMN1; SMN2ALDH1A1MAPTALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2239012-A2 | Pharmaceutical use of substituted amides | High Point Pharmaceuticals, LLC (US) | 2010-10-13 | — | — | EP | claimed |