SCHEMBL346290

SCHEMBL346290

C=C(C(=O)O)C(C)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.39

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.39
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
MMP1 P03956 1/20 0.30
MMP2 P08253 1/20 0.30
MMP9 P14780 1/20 0.30
MMP8 P22894 1/20 0.30
MMP13 P45452 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL870676 1.00 THRB (0.39) THRBCA1CA2MMP1MMP2
SCHEMBL4160742 1.00 THRB (0.39) THRBCA1CA2MMP1MMP2
SCHEMBL17504405 0.98 THRB (0.35) THRBCA1CA2MMP1MMP2
SCHEMBL28684999 0.92 THRB (0.32) THRB
SCHEMBL28679073 0.84 TET2 (0.32)
SCHEMBL8858644 0.80 THRB (0.41) THRBCA1CA2MMP1MMP2
SCHEMBL8858648 0.80 THRB (0.41) THRBCA1CA2MMP1MMP2
SCHEMBL933456 0.79 THRB (0.44) THRBCA1CA2MMP1MMP2
SCHEMBL8985374 0.79 THRB (0.44) THRBCA1CA2MMP1MMP2
SCHEMBL688532 0.78 THRB (0.40) THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090212467-A1 Expandable Bladder PIRELLI PNEUMATICI S.P.A. (IT) 2009-08-27 US claimed
EP-1841576-A1 EXPANDABLE BLADDER Pirelli Tyre S.p.A. (IT) 2007-10-10 EP claimed
WO-2006079359-A1 EXPANDABLE BLADDER PIRELLI TYRE S.P.A. (IT) 2006-08-03 WO claimed
EP-0484163-B1 Liquid crystal display device SHARP KK (JP) 1995-05-03 EP claimed
CN-115160486-A Antibacterial fluorine-containing emulsifier and preparation method thereof 同济大学 2022-10-11 CN disclosed
CN-112236691-B Optical laminate, transfer laminate, and method for producing optical laminate 迪睿合株式会社 2022-09-06 CN disclosed
CN-114685713-A Polymer, electrolyte, and lithium ion battery comprising same 财团法人工业技术研究院 2022-07-01 CN disclosed
CN-109422850-B Self-crosslinking fluorine-containing macromolecular emulsifier, fluorine-containing emulsion containing emulsifier, and preparation and use methods thereof 浙江大学 2021-07-02 CN disclosed
CN-112424649-A Resin laminated optical body, light source unit, method for producing resin laminated optical body, method for producing light source unit, optical unit, light irradiation device, and image display device 迪睿合株式会社 2021-02-26 CN disclosed
CN-112236691-A Optical laminate, transfer laminate, and method for producing optical laminate 迪睿合株式会社 2021-01-15 CN disclosed
US-20120013828-A1 POLARIZING PLATE, METHOD FOR PRODUCING POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE KONICA MINOLTA OPTO, INC. (JP) 2012-01-19 US disclosed
US-20100104879-A1 CLEAR HARD COAT FILM, ANTI-REFLECTION FILM, POLARIZING PLATE AND DISPLAY DEVICE EMPLOYING THE SAME KONICA MINOLTA OPTO, INC. (JP) 2010-04-29 US disclosed
WO-2004102708-A2 PREVENTION OF FLOODING OF FUEL CELL STACK NISSAN MOTOR CO., LTD. (JP) 2004-11-25 WO disclosed
EP-0800118-B1 Carrier for developer of electrostatic latent image, method for making said carrier, developer of electrostatic latent image and method for forming image FUJI XEROX CO LTD (JP) 2004-06-16 EP disclosed
US-20040043320-A1 Dry two-component type developer for electrophotography POWDERTECH CO., LTD. 2004-03-04 US disclosed
EP-1394621-A2 Dry two-component type developer for electrophotography POWDERTECH CO. LTD. (JP) 2004-03-03 EP disclosed
EP-1378769-A2 Water-absorptive contact lens and method of producing the same Menicon Co., Ltd. (JP) 2004-01-07 EP disclosed
US-5849448-A Carrier for developer of electrostatic latent image, method for making said carrier FUJI XEROX CO., LTD. (JP) 1998-12-15 US disclosed
EP-0800118-A1 Carrier for developer of electrostatic latent image, method for making said carrier, developer of electrostatic latent image, method for forming image and apparatus for forming image FUJI XEROX CO., LTD. (JP) 1997-10-08 EP disclosed
US-5643471-A PAIR OF SUBSTRATES HAVING INTERPOSED LIQUID CRYSTAL LAYER, SPACERS COVERED WITH LIGHT-SHIELDING LAYER, LIQUID CRYSTAL MOLECULES IN PIXELS ALIGNED IN AT LEAST TWO DIRECTIONS SHARP KABUSHIKI KAISHA (JP) 1997-07-01 US disclosed