SCHEMBL8985374

SCHEMBL8985374

CC(C(=O)O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.44
CA1 P00915 4/20 0.33
CA2 P00918 4/20 0.33
MMP1 P03956 4/20 0.33
MMP2 P08253 4/20 0.33
MMP9 P14780 4/20 0.33
MMP8 P22894 4/20 0.33
MMP13 P45452 4/20 0.33
TP53 P04637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL933456 1.00 THRB (0.44) THRBCA1CA2MMP1MMP2
SCHEMBL8511154 0.91 THRB (0.37) THRBCA1CA2MMP1MMP2
SCHEMBL8858648 0.83 THRB (0.41) THRBCA1CA2MMP1MMP2
SCHEMBL8858644 0.83 THRB (0.41) THRBCA1CA2MMP1MMP2
SCHEMBL1766346 0.80 TP53 (0.38) TP53
SCHEMBL27096229 0.80 THRB (0.38) THRBCA1CA2MMP1MMP2
SCHEMBL4160742 0.79 THRB (0.39) THRBCA1CA2MMP1MMP2
SCHEMBL346290 0.79 THRB (0.39) THRBCA1CA2MMP1MMP2
SCHEMBL870676 0.79 THRB (0.39) THRBCA1CA2MMP1MMP2
SCHEMBL29098824 0.78 THRB (0.41) THRBCA1CA2MMP1MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120196297-A1 MASS TAGS FOR MASS SPECTROMETRIC ANALYSIS OF IMMUNOGLOBULINS YOST RICHARD A (US) 2012-08-02 US disclosed
US-5491083-A SEPARATION OF BIOMASS, DIAGNOTIC ASSAY, BIOSENSORS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1996-02-13 US disclosed
US-5384254-A For preparation of biosensors for medical diagnosis by immobilization og enzymes or ionic or nonionic groups E. I. DU PONT DE NEMOURS AND COMPANY (US) 1995-01-24 US disclosed
US-5342772-A Activating with a poly(fluoroalkyl)sugar reagent E. I. DU PONT DE NEMOURS AND COMPANY (US) 1994-08-30 US disclosed
US-5306615-A Liquid perfluorocarbon support; fluorinated isocyanate anchor groups E. I. DU PONT DE NEMOURS AND COMPANY (US) 1994-04-26 US disclosed
US-5276146-A Ligand attached to support with isocyanate anchor E. I. DU PONT DE NEMOURS AND COMPANY (US) 1994-01-04 US disclosed
US-5268456-A Immobilizing a protein; bonding to ligand E. I. DU PONT DE NEMOURS AND COMPANY (US) 1993-12-07 US disclosed
US-5268307-A Dissolving a perfluoroisocyanate emulsifier with ligand or binder E. I. DU PONT DE NEMOURS AND COMPANY (US) 1993-12-07 US disclosed
EP-0281368-B1 ENZYME IMMOBILIZATION AND BIOAFFINITY SEPARATIONS WITH PERFLUOROCARBON POLYMER-BASED SUPPORTS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-09-15 EP disclosed
US-5243037-A Compounds for medical diagnosis and biosensors E. I. DU PONT DE NEMOURS AND COMPANY (US) 1993-09-07 US disclosed
EP-0246103-B1 BIOAFFINITY AND ION EXCHANGE SEPARATIONS WITH LIQUID EXCHANGE SUPPORTS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-08-25 EP disclosed
EP-0550479-A1 POLY(FLUOROALKYL) SUGAR REAGENTS AND THEIR USE FOR SURFACE MODIFICATION E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-07-14 EP disclosed
EP-0549665-A1 POLY(FLUOROALKYL) SUGAR REAGENTS AND THEIR USE FOR SURFACE MODIFICATION E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-07-07 EP disclosed
WO-1992005444-A1 POLY(FLUOROALKYL) SUGAR REAGENTS AND THEIR USE FOR SURFACE MODIFICATION E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-04-02 WO disclosed
WO-1992005445-A1 POLY(FLUOROALKYL) SUGAR REAGENTS AND THEIR USE FOR SURFACE MODIFICATION E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-04-02 WO disclosed
US-4954444-A Fluorinated isocyanate anchor E. I. DU PONT DE NEMOURS AND COMPANY (US) 1990-09-04 US disclosed
US-4885250-A FOR COLORIMETRIC AND/OR QUANTITATIVE ANALYSIS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1989-12-05 US disclosed
EP-0281368-A2 Enzyme immobilization and bioaffinity separations with perfluorocarbon polymer-based supports E.I. DU PONT DE NEMOURS AND COMPANY (US) 1988-09-07 EP disclosed
EP-0246103-A2 Bioaffinity and ion exchange separations with liquid exchange supports E.I. DU PONT DE NEMOURS AND COMPANY (US) 1987-11-19 EP disclosed