⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3905017 | 0.74 | — | — | |
| SCHEMBL9042804 | 0.71 | — | — | |
| SCHEMBL6689624 | 0.68 | — | — | |
| SCHEMBL14370712 | 0.65 | — | — | |
| SCHEMBL15215820 | 0.62 | — | — | |
| SCHEMBL22551448 | 0.61 | — | — | |
| SCHEMBL1869258 | 0.61 | — | — | |
| SCHEMBL10948945 | 0.61 | — | — | |
| SCHEMBL2443206 | 0.61 | — | — | |
| SCHEMBL22551463 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1448673-B1 | HIGH REFRACTIVE INDEX AROMATIC-BASED PREPOLYMER PRECURSORS | BAUSCH & LOMB (US) | 2009-02-11 | — | — | EP | claimed |
| US-7132493-B2 | High refractive index aromatic-based prepolymer precursors | BAUSCH & LOMB INCORPORATED (US) | 2006-11-07 | — | — | US | claimed |
| US-20050165246-A1 | High refractive index aromatic-based prepolymer precursors | LAI YU-CHIN (US) | 2005-07-28 | — | — | US | claimed |
| US-20040155373-A1 | High refractive index aromatic-based prepolymer precursors | BAUSCH HEALTH, CANADA INC. / SANTE BAUSCH, CANADA INC. (CA) | 2004-08-12 | — | — | US | claimed |
| US-20040158020-A1 | High refractive index aromatic-based prepolymer precursors | SOLTA MEDICAL DUTCH HOLDINGS B.V. (NL) | 2004-08-12 | — | — | US | claimed |
| US-20040158019-A1 | High refractive index aromatic-based prepolymer precursors | LAI YU-CHIN (US) | 2004-08-12 | — | — | US | claimed |
| US-20030130465-A1 | High refractive index aromatic-based prepolymer precursors | BAUSCH HEALTH IRELAND LIMITED (F/K/A/ VALEANT PHARMACEUTICALS IRELAND LIMITED) (IE) | 2003-07-10 | — | — | US | claimed |
| EP-3303447-B1 | SYNTHESIS OF POLYCARBONATE SILOXANE DIOLS | RUA LIFE SCIENCES PLC (GB) | 2024-05-29 | — | — | EP | disclosed |
| CN-110177822-B | Synthesis of polycarbonate siloxane diol | 奥特克国际公开有限公司 | 2022-06-14 | — | — | CN | disclosed |
| EP-3302589-B1 | PROCESS FOR THE PREPARATION OF POLYURETHANE SOLUTIONS BASED ON SILICON-POLYCARBONATE DIOLS | RUA LIFE SCIENCES PLC (GB) | 2021-08-11 | — | — | EP | disclosed |
| US-10730994-B2 | Synthesis of polycarbonate siloxane diols | AORTECH INTERNATIONAL PLC (GB) | 2020-08-04 | — | — | US | disclosed |
| US-10655012-B2 | Process for the preparation of polyurethane solutions based on silicon-polycarbonate diols | AORTECH INTERNATIONAL PLC (GB) | 2020-05-19 | — | — | US | disclosed |
| US-20200032055-A1 | PROCESS FOR THE PREPARATION OF POLYURETHANE SOLUTIONS BASED ON SILICONPOLYCARBONATE DIOLS | AORTECH INTERNATIONAL PLC (GB) | 2020-01-30 | — | — | US | disclosed |
| US-7026423-B2 | Silicon-based polycarbonates | AORTECH BIOMATERIALS PTY LTD. (AU) | 2006-04-11 | — | — | US | disclosed |
| US-20050288466-A1 | Novel prepolymers for improved surface modification of contact lenses | BAUSCH HEALTH US, LLC | 2005-12-29 | — | — | US | disclosed |
| US-20030092864-A1 | Silicon-based polycarbonates | AORTECH BIOMATERIALS PTY LTD. | 2003-05-15 | — | — | US | disclosed |
| EP-0984997-B1 | SILICON-BASED POLYCARBONATES | AORTECH BIOMATERIALS PTY LTD (AU) | 2002-09-18 | — | — | EP | disclosed |
| EP-0984997-A4 | SILICON-BASED POLYCARBONATES | CARDIAC CRC NOMINEES PTY LTD (AU) | 2000-03-29 | — | — | EP | disclosed |
| EP-0984997-A1 | SILICON-BASED POLYCARBONATES | CARDIAC CRC NOMINEES PTY. LTD. (AU) | 2000-03-15 | — | — | EP | disclosed |
| WO-1998054242-A1 | SILICON-BASED POLYCARBONATES | CARDIAC CRC NOMINEES PTY. LTD. (AU) | 1998-12-03 | — | — | WO | disclosed |