SCHEMBL3905017

SCHEMBL3905017

CCCC(O)[Si](C)(C)O[SiH](C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1666609 0.83
SCHEMBL29616833 0.77
SCHEMBL1130557 0.77 LMNA (0.31)
SCHEMBL3462954 0.74
SCHEMBL9042804 0.71
SCHEMBL3957807 0.68
SCHEMBL15215820 0.67
SCHEMBL6664579 0.67
SCHEMBL2305407 0.66
SCHEMBL14370712 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1448673-B1 HIGH REFRACTIVE INDEX AROMATIC-BASED PREPOLYMER PRECURSORS BAUSCH & LOMB (US) 2009-02-11 EP disclosed
US-7132493-B2 High refractive index aromatic-based prepolymer precursors BAUSCH & LOMB INCORPORATED (US) 2006-11-07 US disclosed
US-6951914-B2 High refractive index aromatic-based prepolymer precursors BAUSCH & LOMB INCORPORATED (US) 2005-10-04 US disclosed
US-6864341-B2 High refractive index aromatic-based prepolymer precursors BAUSCH & LOMB INCORPORATED (US) 2005-03-08 US disclosed
US-20040254326-A1 High refractive index aromatic-based prepolymers PRZEDSIEBIORSTWO FARMACEUTYCZNE JELFA SPOLKA AKCYJNA (A/K/A PRZEDSIEBIORSTWO FARMACEUTYCZNE JELFA S.A.) (PL) 2004-12-16 US disclosed
EP-1448673-A1 HIGH REFRACTIVE INDEX AROMATIC-BASED PREPOLYMER PRECURSORS Bausch & Lomb Incorporated (US) 2004-08-25 EP disclosed
US-6777522-B2 COPOLYMERIZATION OF ONE OR MORE AROMATIC-SUBSTITUTED POLYSILOXANE PREPOLYMERS WITH ONE OR MORE UNSATURATED MONOMERS, ESPECIALLY ACRYLIC MONOMERS; INTRAOCULAR LENSES AND CORNEAL INLAYS BAUSCH & LOMB INCORPORATED 2004-08-17 US disclosed
US-20040158020-A1 High refractive index aromatic-based prepolymer precursors SOLTA MEDICAL DUTCH HOLDINGS B.V. (NL) 2004-08-12 US disclosed
EP-1444275-A1 HIGH REFRACTIVE INDEX AROMATIC-BASED PREPOLYMERS BAUSCH & LOMB INCORPORATED (US) 2004-08-11 EP disclosed
US-20030134977-A1 High refractive index aromatic-based prepolymers PRZEDSIEBIORSTWO FARMACEUTYCZNE JELFA SPOLKA AKCYJNA (A/K/A PRZEDSIEBIORSTWO FARMACEUTYCZNE JELFA S.A.) (PL) 2003-07-17 US disclosed
US-20030130465-A1 High refractive index aromatic-based prepolymer precursors BAUSCH HEALTH IRELAND LIMITED (F/K/A/ VALEANT PHARMACEUTICALS IRELAND LIMITED) (IE) 2003-07-10 US disclosed
WO-2003040200-A1 HIGH REFRACTIVE INDEX AROMATIC-BASED PREPOLYMERS BAUSCH & LOMB INCORPORATED (US) 2003-05-15 WO disclosed
WO-2003040214-A1 HIGH REFRACTIVE INDEX AROMATIC-BASED PREPOLYMER PRECURSORS BAUSCH & LOMB INCORPORATED (US) 2003-05-15 WO disclosed