Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX1 | Q96LB2 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | F2 | P00734 | 1/20 | 0.52 |
| ▸ | F10 | P00742 | 1/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.52 |
| ▸ | F7 | P08709 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | BCHE | P06276 | 2/20 | 0.50 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3463524 | 0.87 | MAPT (0.55) | KMT2AMEN1SMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL4686919 | 0.77 | MEN1 (0.54) | LMNAKMT2AMEN1SMN1; SMN2L3MBTL1 | |
| SCHEMBL31192466 | 0.77 | MRGPRX1 (0.74) | MRGPRX1LMNAF2F10PRSS1 | |
| SCHEMBL2676462 | 0.77 | ELANE (0.65) | KMT2ASMN1; SMN2ALDH1A1GAABCHE | |
| SCHEMBL3463497 | 0.76 | NPC1 (0.81) | MRGPRX1LMNAF2F10PRSS1 | |
| SCHEMBL28659168 | 0.75 | LMNA (0.61) | MRGPRX1LMNAF2F10PRSS1 | |
| SCHEMBL5525095 | 0.74 | BCHE (0.64) | MRGPRX1LMNAF2F10PRSS1 | |
| SCHEMBL3051565 | 0.74 | LMNA (0.74) | MRGPRX1LMNAF2F10PRSS1 | |
| SCHEMBL6090056 | 0.74 | ELANE (0.49) | LMNAKMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL9416614 | 0.73 | LMNA (0.73) | MRGPRX1LMNAF2F10PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010010435-A2 | FUSED OXAZOLE AND THIAZOLE DERIVATIVES AS TRPMS MODULATORS | GLENMARK PHARMACEUTICAL S.A. (CH) | 2010-01-28 | — | — | WO | disclosed |
| WO-2010010435-A2 | FUSED OXAZOLE AND THIAZOLE DERIVATIVES AS TRPMS MODULATORS | GLENMARK PHARMACEUTICAL S.A. (CH) | 2010-01-28 | — | — | WO | disclosed |