Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.70 |
| ▸ | BCHE | P06276 | 2/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.70 |
| ▸ | HTT | P42858 | 2/20 | 0.70 |
| ▸ | NPY1R | P25929 | 1/20 | 0.70 |
| ▸ | NPY2R | P49146 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | ATM | Q13315 | 1/20 | 0.64 |
| ▸ | HTR1A | P08908 | 1/20 | 0.62 |
| ▸ | HTR7 | P34969 | 1/20 | 0.62 |
| ▸ | HTR6 | P50406 | 1/20 | 0.62 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.61 |
| ▸ | MRGPRX1 | Q96LB2 | 2/20 | 0.61 |
| ▸ | F2 | P00734 | 1/20 | 0.61 |
| ▸ | F10 | P00742 | 1/20 | 0.61 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.61 |
| ▸ | F7 | P08709 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3051565 | 0.95 | LMNA (0.74) | LMNASMN1; SMN2KMT2ABCHEKDM4E | |
| SCHEMBL13973184 | 0.90 | BCHE (0.69) | LMNASMN1; SMN2KMT2ABCHEKDM4E | |
| Hydrochloric Acid SCHEMBL4949263 | 0.90 | BCHE (0.77) | LMNASMN1; SMN2KMT2ABCHEKDM4E | |
| SCHEMBL5114841 | 0.89 | LMNA (0.67) | LMNASMN1; SMN2KMT2ABCHEKDM4E | |
| SCHEMBL3042373 | 0.88 | LMNA (0.69) | LMNASMN1; SMN2KMT2ABCHEKDM4E | |
| SCHEMBL5525095 | 0.87 | BCHE (0.64) | LMNASMN1; SMN2KMT2ABCHEKDM4E | |
| SCHEMBL31192440 | 0.86 | BCHE (0.65) | LMNASMN1; SMN2KMT2ABCHEKDM4E | |
| SCHEMBL31192444 | 0.85 | BCHE (0.63) | LMNASMN1; SMN2KMT2ABCHEKDM4E | |
| SCHEMBL28312735 | 0.85 | LMNA (0.63) | LMNASMN1; SMN2KMT2ABCHEKDM4E | |
| SCHEMBL4812481 | 0.85 | LMNA (0.63) | LMNASMN1; SMN2KMT2ABCHEKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0613879-A1 | PHELLODENDRINE ANALOGS AND ALLERGY TYPE IV SUPPRESSOR CONTAINING THE SAME AS ACTIVE INGREDIENT | TSUMURA & CO. (JP) | 1994-09-07 | — | — | EP | disclosed |