Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.42 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 9/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.37 |
| ▸ | RRM1 | P23921 | 1/20 | 0.34 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.33 |
| ▸ | CASP2 | P42575 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8815454 | 0.87 | ZDHHC20 (0.46) | ZDHHC20ZDHHC2EPHX1DPP7TSHR | |
| SCHEMBL11090017 | 0.81 | EPHX1 (0.41) | EPHX1DPP7RRM1TSHRCASP2 | |
| SCHEMBL3737147 | 0.75 | TSHR (0.41) | ZDHHC20ZDHHC2EPHX1TSHRHPGD | |
| SCHEMBL2490188 | 0.75 | ZDHHC20 (0.40) | ZDHHC20ZDHHC2EPHX1 | |
| SCHEMBL3332206 | 0.71 | ABCB1 (0.40) | ZDHHC20ZDHHC2TSHRHPGDFAAH | |
| SCHEMBL28160040 | 0.70 | ZDHHC20 (0.46) | ZDHHC20ZDHHC2EPHX1TSHR | |
| SCHEMBL278531 | 0.70 | TSHR (0.37) | TSHRHPGD | |
| SCHEMBL24846447 | 0.69 | EPHX1 (0.45) | ZDHHC20ZDHHC2EPHX1DPP7RRM1 | |
| SCHEMBL4354667 | 0.69 | ZDHHC20 (0.42) | ZDHHC20ZDHHC2EPHX1DPP7TSHR | |
| SCHEMBL299757 | 0.69 | ZDHHC20 (0.42) | ZDHHC20ZDHHC2EPHX1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010010435-A2 | FUSED OXAZOLE AND THIAZOLE DERIVATIVES AS TRPMS MODULATORS | GLENMARK PHARMACEUTICAL S.A. (CH) | 2010-01-28 | — | — | WO | disclosed |