Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.42 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 9/20 | 0.41 |
| ▸ | ADH1B | P00325 | 2/20 | 0.41 |
| ▸ | ADH1C | P00326 | 2/20 | 0.41 |
| ▸ | ADH1A | P07327 | 2/20 | 0.41 |
| ▸ | ADH7 | P40394 | 2/20 | 0.41 |
| ▸ | ADH4 | P08319 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | CASP2 | P42575 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1493994 | 0.74 | EPHX1 (0.41) | ZDHHC20ZDHHC2EPHX1ADH1BADH1C | |
| SCHEMBL299757 | 0.74 | ZDHHC20 (0.42) | ZDHHC20ZDHHC2EPHX1ADH1BADH1C | |
| SCHEMBL5669161 | 0.74 | TSHR (0.39) | ZDHHC20ZDHHC2EPHX1ADH1BADH1C | |
| SCHEMBL9579992 | 0.74 | TSHR (0.39) | ZDHHC20ZDHHC2EPHX1ADH1BADH1C | |
| SCHEMBL7650979 | 0.74 | TSHR (0.39) | ZDHHC20ZDHHC2EPHX1ADH1BADH1C | |
| SCHEMBL23889733 | 0.72 | ZDHHC20 (0.37) | ZDHHC20ZDHHC2EPHX1ADH1BADH1C | |
| Hydrochloric Acid SCHEMBL22771812 | 0.72 | ZDHHC20 (0.37) | ZDHHC20ZDHHC2EPHX1ADH1BADH1C | |
| SCHEMBL22236421 | 0.72 | ZDHHC20 (0.37) | ZDHHC20ZDHHC2EPHX1ADH1BADH1C | |
| SCHEMBL7648112 | 0.72 | ZDHHC20 (0.41) | ZDHHC20ZDHHC2EPHX1ADH1BADH1C | |
| SCHEMBL3796968 | 0.72 | ZDHHC20 (0.41) | ZDHHC20ZDHHC2EPHX1ADH1BADH1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090312318-A1 | THERAPEUTIC COMPOUNDS AND METHODS | GILEAD SCIENCES, INC. | 2009-12-17 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090312318-A1 | THERAPEUTIC COMPOUNDS AND METHODS | SERPINB1, ABCC1, SERPINB6 | ZDHHC20 3498/4885ZDHHC2 3209/4885EPHX1 1028/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.