Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.36 |
| ▸ | NMT2 | O60551 | 3/20 | 0.34 |
| ▸ | NMT1 | P30419 | 3/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3464354 | 1.00 | CYP2D6 (0.42) | CYP2D6CYP2C19POLBGLO1NMT2 | |
| SCHEMBL22187020 | 0.79 | TSHR (0.42) | CYP2D6CYP2C19POLBALDH1A1KDM4E | |
| SCHEMBL638626 | 0.78 | POLB (0.39) | POLBTP53BP1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL1143034 | 0.78 | POLB (0.39) | POLBTP53BP1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL3463575 | 0.78 | CYP2D6 (0.45) | CYP2D6CYP2C19GLO1NMT2NMT1 | |
| SCHEMBL3463579 | 0.78 | CYP2D6 (0.45) | CYP2D6CYP2C19GLO1NMT2NMT1 | |
| SCHEMBL22874083 | 0.78 | CYP2D6 (0.49) | CYP2D6CYP2C19GLO1MAPTFAAH | |
| SCHEMBL374982 | 0.78 | CYP2D6 (0.49) | CYP2D6CYP2C19GLO1MAPTFAAH | |
| SCHEMBL10941100 | 0.77 | TP53BP1 (0.33) | POLBTP53BP1RAB9A | |
| SCHEMBL23794726 | 0.76 | CYP2D6 (0.48) | CYP2D6CYP2C19GLO1MAPTFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2111391-B9 | NEW UNSATURATED FATTY AMINO-ACID DERIVATIVES AND USE THEREOF IN DERMAL COSMETOLOGY | FABRE PIERRE DERMO COSMETIQUE (FR) | 2013-05-29 | — | — | EP | claimed |
| EP-2111391-B1 | NEW UNSATURATED FATTY AMINO-ACID DERIVATIVES AND USE THEREOF IN DERMAL COSMETOLOGY | FABRE PIERRE DERMO COSMETIQUE (FR) | 2012-10-31 | — | — | EP | claimed |
| US-20100240754-A1 | UNSATURATED FATTY AMINO ACID DERIVATIVES AND USE THEREOF IN DERMAL COSMETOLOGY | Pierre Fabre Demo-Cosmetique (FR) | 2010-09-23 | — | — | US | claimed |
| US-20100240754-A1 | UNSATURATED FATTY AMINO ACID DERIVATIVES AND USE THEREOF IN DERMAL COSMETOLOGY | Pierre Fabre Demo-Cosmetique (FR) | 2010-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100240754-A1 | UNSATURATED FATTY AMINO ACID DERIVATIVES AND USE THEREOF IN DERMAL COSMETOLOGY | FFAR3, FFAR2, BCAT1 | CYP2D6 507/4885CYP2C19 1923/4885POLB 1666/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.