Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 12/20 | 0.69 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.69 |
| ▸ | SERPINA6 | P08185 | 6/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.69 |
| ▸ | SHBG | P04278 | 4/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.69 |
| ▸ | LMNA | P02545 | 4/20 | 0.69 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.69 |
| ▸ | TSHR | P16473 | 2/20 | 0.69 |
| ▸ | BLM | P54132 | 2/20 | 0.69 |
| ▸ | NR3C1 | P04150 | 7/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | PGR | P06401 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL792845 | 1.00 | HSD17B10 (0.69) | HSD17B10HIF1ASERPINA6CYP2C19SHBG | |
| SCHEMBL23645479 | 1.00 | HSD17B10 (0.69) | HSD17B10HIF1ASERPINA6CYP2C19SHBG | |
| SCHEMBL2596391 | 1.00 | HSD17B10 (0.69) | HSD17B10HIF1ASERPINA6CYP2C19SHBG | |
| SCHEMBL10425177 | 0.90 | HSD17B10 (0.69) | HSD17B10HIF1ASERPINA6CYP2C19SHBG | |
| SCHEMBL4622891 | 0.88 | SHBG (0.55) | HSD17B10HIF1ASERPINA6CYP2C19SHBG | |
| SCHEMBL3777671 | 0.88 | LMNA (0.67) | HSD17B10HIF1ASERPINA6CYP2C19SHBG | |
| SCHEMBL26133325 | 0.88 | SHBG (0.55) | HSD17B10HIF1ASERPINA6CYP2C19SHBG | |
| SCHEMBL4622887 | 0.88 | SHBG (0.55) | HSD17B10HIF1ASERPINA6CYP2C19SHBG | |
| SCHEMBL3777666 | 0.88 | LMNA (0.67) | HSD17B10HIF1ASERPINA6CYP2C19SHBG | |
| SCHEMBL10886530 | 0.87 | HIF1A (0.61) | HSD17B10HIF1ASERPINA6CYP2C19SHBG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2201371-A1 | HIGH THROUGHPUT ASSAYS FOR INHIBITORS AND ACTIVATORS OF PAQR RECEPTORS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2010-06-30 | — | — | EP | disclosed |
| WO-2009042561-A1 | HIGH THROUGHPUT ASSAYS FOR INHIBITORS AND ACTIVATORS OF PAQR RECEPTORS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2009-04-02 | — | — | WO | disclosed |