Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.31 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.30 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3465166 | 0.71 | HSP90AA1 (0.38) | PI4K2APLAUMAP3K14HSP90AA1HSP90AB1 | |
| SCHEMBL3463800 | 0.62 | HSP90AA1 (0.44) | HSP90AA1HSP90AB1 | |
| SCHEMBL9089860 | 0.61 | ERN1 (0.39) | DYRK1A | |
| SCHEMBL3464730 | 0.59 | HSP90AA1 (0.40) | HSP90AA1HSP90AB1 | |
| SCHEMBL24469692 | 0.58 | HTR2A (0.39) | DYRK1A | |
| SCHEMBL3463711 | 0.58 | PRKCI (0.35) | HSP90AA1HSP90AB1DYRK1A | |
| SCHEMBL25237748 | 0.56 | RNASEH1 (0.55) | — | |
| SCHEMBL29010833 | 0.55 | PLA2G10 (0.39) | PI4K2APLAUMAP3K14DYRK1A | |
| SCHEMBL29010829 | 0.55 | PLA2G10 (0.39) | PI4K2APLAUMAP3K14DYRK1A | |
| SCHEMBL10460145 | 0.55 | GSK3B (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100240656-A1 | COMPOUNDS AS HSP90 INHIBITORS | ORYZON GENOMICS, S.A. (ES) | 2010-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100240656-A1 | COMPOUNDS AS HSP90 INHIBITORS | HSP90AB1, HSP90AB2P, HSP90AA1 | PI4K2A 3844/4885PLAU 4872/4885MAP3K14 712/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.