Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.53 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 11/20 | 0.34 |
| ▸ | CA1 | P00915 | 10/20 | 0.34 |
| ▸ | CA9 | Q16790 | 10/20 | 0.33 |
| ▸ | CA12 | O43570 | 7/20 | 0.33 |
| ▸ | CA6 | P23280 | 3/20 | 0.33 |
| ▸ | CA5A | P35218 | 3/20 | 0.33 |
| ▸ | CA7 | P43166 | 3/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.33 |
| ▸ | CA3 | P07451 | 3/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.33 |
| ▸ | CA4 | P22748 | 2/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.31 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13368201 | 0.82 | APLNR (0.55) | APLNRPIK3CDPIK3CGCA2CA1 | |
| SCHEMBL3466366 | 0.81 | APLNR (0.50) | APLNRPIK3CDPIK3CGCA2CA1 | |
| SCHEMBL29110465 | 0.81 | APLNR (0.53) | APLNRPIK3CDPIK3CGCA2CA1 | |
| SCHEMBL14159420 | 0.79 | APLNR (0.52) | APLNRPIK3CDPIK3CGCA2CA1 | |
| SCHEMBL11690551 | 0.79 | APLNR (0.71) | APLNRPIK3CDPIK3CGCA2CA1 | |
| SCHEMBL3465097 | 0.78 | APLNR (0.55) | APLNRPIK3CDPIK3CGCA2CA1 | |
| SCHEMBL3465684 | 0.78 | APLNR (0.46) | APLNRPIK3CDPIK3CGCA2CA1 | |
| SCHEMBL31028721 | 0.74 | APLNR (0.59) | APLNRPIK3CDPIK3CGCA2CA1 | |
| SCHEMBL5149401 | 0.74 | APLNR (0.59) | APLNRPIK3CDPIK3CGCA2CA1 | |
| SCHEMBL3465378 | 0.73 | APLNR (0.49) | APLNRPIK3CDPIK3CGCA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8338610-B2 | Pyridinyl compounds useful as intermediates | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-12-25 | — | — | US | disclosed |
| US-20120136158-A1 | Pyridinyl Compounds Useful As Intermediates | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-05-31 | — | — | US | disclosed |
| US-20100093724-A1 | Azaindazole Compounds As CCR1 Receptor Antagonists | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100093724-A1 | Azaindazole Compounds As CCR1 Receptor Antagonists | CCR1, CCR3, CCR4 | APLNR 2127/4885PIK3CD 4069/4885PIK3CG 4598/4885 |
| US-20120136158-A1 | Pyridinyl Compounds Useful As Intermediates | CCR1, CCRL2, CCR4 | APLNR 2724/4885PIK3CD 3284/4885PIK3CG 3407/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.