SCHEMBL3465394

SCHEMBL3465394

Cc1cccc(C(=O)O)c1OC1CCCCC1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CXCR5 P32302 4/20 0.55
ALDH1A1 P00352 3/20 0.54
KDM4E B2RXH2 2/20 0.54
HPGD P15428 2/20 0.54
HSD17B10 Q99714 2/20 0.54
PDE4A P27815 3/20 0.43
PDE4B Q07343 3/20 0.43
PDE4C Q08493 3/20 0.43
PDE4D Q08499 3/20 0.43
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
KMT2A Q03164 1/20 0.42
CNR1 P21554 1/20 0.41
CNR2 P34972 1/20 0.41
MYC P01106 1/20 0.41
THRA P10827 1/20 0.40
THRB P10828 1/20 0.40
MAOB P27338 1/20 0.40
ATM Q13315 1/20 0.40
MAPK1 P28482 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3306602 0.95 CXCR5 (0.59) CXCR5ALDH1A1KDM4EHPGDHSD17B10
SCHEMBL3309536 0.86 CXCR5 (0.52) CXCR5ALDH1A1KDM4EHPGDHSD17B10
SCHEMBL29050940 0.85 CXCR5 (0.53) CXCR5ALDH1A1KDM4EHPGDHSD17B10
SCHEMBL12760784 0.83 ALDH1A1 (0.43) CXCR5ALDH1A1KDM4EHPGDHSD17B10
SCHEMBL5791812 0.82 ALB (0.45) CXCR5PDE4APDE4BPDE4CPDE4D
SCHEMBL11587469 0.82 HTR1A (0.45) CXCR5PDE4APDE4BPDE4CPDE4D
SCHEMBL10590612 0.81 PTGDR2 (0.43) CXCR5ALDH1A1KDM4EHPGDHSD17B10
SCHEMBL27906539 0.81 KMT2A (0.41) CXCR5ALDH1A1KDM4EHPGDHSD17B10
SCHEMBL13328396 0.81 CXCR5 (0.57) CXCR5ALDH1A1KDM4EHPGDHSD17B10
SCHEMBL9005689 0.79 PTGER1 (0.47) ALDH1A1PDE4APDE4BPDE4CPDE4D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014090524-A2 ACTIVE SUBSTANCE COMBINATION FOR SKIN LIGHTENING II HENKEL AG & CO. KGAA (DE) 2014-06-19 WO disclosed
WO-2012011908-A1 COMPOSITIONS AND METHODS FOR INHIBITING PAR2 ACTIVATION OF KERATINOCYTES THE PROCTER & GAMBLE COMPANY (US) 2012-01-26 WO disclosed
EP-2150230-A1 CLEANSING OIL-IN-WATER EMULSIONS Henkel AG & Co. KGaA (DE) 2010-02-10 EP disclosed
EP-2144597-A1 OIL-IN-WATER EMULSIONS II WHICH ARE STABILIZED BY THEIR ACTIVE INGREDIENT Henkel AG & Co. KGaA (DE) 2010-01-20 EP disclosed
WO-2008104215-A1 OIL-IN-WATER EMULSIONS II WHICH ARE STABILIZED BY THEIR ACTIVE INGREDIENT HENKEL AG & CO. KGAA (DE) 2008-09-04 WO disclosed
WO-2008104214-A1 CLEANSING OIL-IN-WATER EMULSIONS HENKEL AG & CO. KGAA (DE) 2008-09-04 WO disclosed
WO-2000069406-A1 METHODS OF REGULATING THE CONDITION OF MAMMALIAN KERATINOUS TISSUE THE PROCTER & GAMBLE COMPANY (US) 2000-11-23 WO disclosed