Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | NAMPT | P43490 | 3/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.32 |
| ▸ | FPR2 | P25090 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25961260 | 0.87 | CA2 (0.44) | CA2ALDH1A1NPSR1TMEM97SIGMAR1 | |
| SCHEMBL28924707 | 0.87 | CA2 (0.44) | CA2ALDH1A1NPSR1TMEM97SIGMAR1 | |
| SCHEMBL15786354 | 0.87 | CA2 (0.44) | CA2ALDH1A1NPSR1TMEM97SIGMAR1 | |
| SCHEMBL18817554 | 0.84 | CTDSP1 (0.43) | CA2ALDH1A1NPSR1TMEM97SIGMAR1 | |
| SCHEMBL1243777 | 0.84 | CTDSP1 (0.43) | CA2ALDH1A1NPSR1TMEM97SIGMAR1 | |
| SCHEMBL28924704 | 0.83 | CA2 (0.41) | CA2ALDH1A1NPSR1TMEM97SIGMAR1 | |
| SCHEMBL28924703 | 0.83 | CA2 (0.41) | CA2ALDH1A1NPSR1TMEM97SIGMAR1 | |
| SCHEMBL7157022 | 0.81 | CA2 (0.44) | CA2ALDH1A1NPSR1TMEM97SIGMAR1 | |
| SCHEMBL5316548 | 0.81 | CA2 (0.44) | CA2ALDH1A1NPSR1TMEM97SIGMAR1 | |
| SCHEMBL7154220 | 0.81 | CA2 (0.44) | CA2ALDH1A1NPSR1TMEM97SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010029574-A2 | AN IMPROVED PROCESS FOR THE PREPARATION OF GEMCITABINE AND ITS INTERMEDIATES USING NOVEL PROTECTING GROUPS AND ION EXCHANGE RESINS | KANNAN VISHWANATH (IN) | 2010-03-18 | — | — | WO | disclosed |