Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1243777 | 1.00 | CTDSP1 (0.43) | CTDSP1CA2ALDH1A1NPSR1USP2 | |
| SCHEMBL28924707 | 0.84 | CA2 (0.44) | CA2ALDH1A1NPSR1TSHRTMEM97 | |
| SCHEMBL3465823 | 0.84 | CA2 (0.44) | CTDSP1CA2ALDH1A1NPSR1TMEM97 | |
| SCHEMBL25961260 | 0.84 | CA2 (0.44) | CA2ALDH1A1NPSR1TSHRTMEM97 | |
| SCHEMBL10314728 | 0.84 | CTDSP1 (0.45) | CTDSP1CA2ALDH1A1NPSR1ALOX15 | |
| SCHEMBL1859536 | 0.84 | CTDSP1 (0.45) | CTDSP1CA2ALDH1A1NPSR1ALOX15 | |
| SCHEMBL15786354 | 0.84 | CA2 (0.44) | CA2ALDH1A1NPSR1TSHRTMEM97 | |
| SCHEMBL10314726 | 0.84 | CTDSP1 (0.45) | CTDSP1CA2ALDH1A1NPSR1ALOX15 | |
| SCHEMBL21136085 | 0.84 | CA2 (0.46) | CTDSP1CA2CYP1A2LMNAPOLB | |
| SCHEMBL15343421 | 0.82 | CA2 (0.44) | CTDSP1CA2ALDH1A1NPSR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3882246-A1 | MONOBACTAM COMPOUNDS AND USE THEREFOR | Nanjing Sanhome Pharmaceutical Co., Ltd. (CN) | 2021-09-22 | — | — | EP | disclosed |
| WO-2020098635-A1 | MONOBACTAM COMPOUNDS AND USE THEREFOR | 南京圣和药业股份有限公司 | 2020-05-22 | — | — | WO | disclosed |
| WO-2017075590-A2 | PROCESSES FOR PREPARING 2-DIHALO RIBOLACTONES | COCRYSTAL PHARMA, INC. (US) | 2017-05-04 | — | — | WO | disclosed |