Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.45 |
| ▸ | MEN1 | O00255 | 6/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | GRM8 | O00222 | 1/20 | 0.45 |
| ▸ | GRM6 | O15303 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | PPM1B | O75688 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1454771 | 0.82 | ALDH1A1 (0.55) | TDP1KMT2AMEN1HSD17B10CYP2C9 | |
| SCHEMBL23005779 | 0.82 | ALDH1A1 (0.51) | TDP1KMT2AMEN1HSD17B10CYP2C9 | |
| SCHEMBL27553352 | 0.79 | ALDH1A1 (0.50) | TDP1KMT2AMEN1HSD17B10CYP2C9 | |
| SCHEMBL20793894 | 0.77 | ALDH1A1 (0.50) | TDP1KMT2AMEN1HSD17B10CYP2C9 | |
| SCHEMBL22471781 | 0.76 | ALDH1A1 (0.46) | TDP1KMT2AMEN1HSD17B10CYP2C9 | |
| SCHEMBL28271886 | 0.75 | ALDH1A1 (0.45) | TDP1KMT2AMEN1HSD17B10CYP2C9 | |
| SCHEMBL2008242 | 0.74 | ALDH1A1 (0.55) | TDP1KMT2AMEN1HSD17B10CYP2C9 | |
| SCHEMBL23005781 | 0.71 | ALDH1A1 (0.57) | TDP1KMT2AMEN1HSD17B10CYP2C9 | |
| SCHEMBL15543858 | 0.71 | TSHR (0.50) | KMT2AALDH1A1HPGDALOX15 | |
| SCHEMBL9174867 | 0.70 | ALDH1A1 (0.55) | TDP1KMT2AMEN1HSD17B10CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016193062-A1 | POLYMERIC, UNATTACHED ADDITIVE FOR INCREASING DIELECTRIC CONSTANT IN ELECTROACTIVE POLYURETHANE POLYMERS | COVESTRO DEUTSCHLAND AG (DE) | 2016-12-08 | — | — | WO | disclosed |
| EP-2262842-A2 | 2,2'-MDI-BASED ISOCYANATE MIXTURES AND THE PRODUCTION AND USE THEREOF | Bayer MaterialScience AG (DE) | 2010-12-22 | — | — | EP | disclosed |
| WO-2009118112-A2 | 2,2'-MDI-BASED ISOCYANATE MIXTURES AND THE PRODUCTION AND USE THEREOF | BAYER MATERIALSCIENCE AG (DE) | 2009-10-01 | — | — | WO | disclosed |