SCHEMBL2008242

SCHEMBL2008242

CC(c1ccc(C(=O)O)c(N)c1)[N+](=O)[O-]

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.55
TDP1 Q9NUW8 5/20 0.55
CYP3A4 P08684 1/20 0.55
ALOX15 P16050 1/20 0.55
PPM1B O75688 1/20 0.43
KDM4E B2RXH2 5/20 0.41
HSD17B10 Q99714 4/20 0.41
HPGD P15428 3/20 0.41
KMT2A Q03164 7/20 0.40
GFER P55789 1/20 0.40
RXFP1 Q9HBX9 1/20 0.40
MEN1 O00255 6/20 0.39
CYP2C9 P11712 2/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C19 P33261 1/20 0.39
GRM8 O00222 1/20 0.39
GRM6 O15303 1/20 0.39
SLC6A2 P23975 1/20 0.39
SLC6A4 P31645 1/20 0.39
DRD3 P35462 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23005779 0.80 ALDH1A1 (0.51) ALDH1A1TDP1CYP3A4ALOX15PPM1B
SCHEMBL1454771 0.80 ALDH1A1 (0.55) ALDH1A1TDP1CYP3A4ALOX15PPM1B
SCHEMBL27553352 0.77 ALDH1A1 (0.50) ALDH1A1TDP1CYP3A4ALOX15PPM1B
SCHEMBL20793894 0.74 ALDH1A1 (0.50) ALDH1A1TDP1CYP3A4ALOX15PPM1B
SCHEMBL3466210 0.74 TDP1 (0.45) ALDH1A1TDP1CYP3A4ALOX15PPM1B
SCHEMBL22471781 0.73 ALDH1A1 (0.46) ALDH1A1TDP1CYP3A4ALOX15PPM1B
SCHEMBL11194625 0.73 TDP1 (0.39) ALDH1A1TDP1CYP3A4ALOX15KDM4E
SCHEMBL3390980 0.73 TDP1 (0.52) ALDH1A1TDP1KMT2AMEN1HCAR3
Isobutyramide SCHEMBL1985133 0.73 ALDH1A1 (0.79) ALDH1A1TDP1CYP3A4ALOX15KMT2A
SCHEMBL28271886 0.72 ALDH1A1 (0.45) ALDH1A1TDP1CYP3A4ALOX15PPM1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7960181-B2 Chromoionophore and method of determining potassium ions OPTI MEDICAL SYSTEMS (US) 2011-06-14 US disclosed
WO-2007131042-A2 CHROMOIONOPHORE AND METHOD OF DETERMINING POTASSIUM IONS OPTI MEDICAL SYSTEMS, INC (US) 2007-11-15 WO disclosed
US-20070259443-A1 CHROMOIONOPHORE AND METHOD OF DETERMINING POTASSIUM IONS OPTI MEDICAL SYSTEMS, INC. 2007-11-08 US disclosed