Iodide

Iodide

SCHEMBL3466445

C=CCC(CC=C)C(N)c1ccccc1.I

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG

The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 2/20 0.50
CYP2C19 P33261 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.43
F2 P00734 1/20 0.39
ALDH1A1 P00352 2/20 0.39
KDM4E B2RXH2 1/20 0.39
MAPT P10636 1/20 0.39
ALOX15 P16050 1/20 0.39
HSD17B10 Q99714 1/20 0.39
HTR2A P28223 2/20 0.37
TAAR1 Q96RJ0 1/20 0.37
ATM Q13315 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
HRH1 P35367 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1678152 0.98 DPP4 (0.52) DPP4CYP2C19SMN1; SMN2F2ALDH1A1
Bromide SCHEMBL3466618 0.96 DPP4 (0.50) DPP4CYP2C19SMN1; SMN2F2ALDH1A1
Hydrochloric Acid SCHEMBL327082 0.96 DPP4 (0.50) DPP4CYP2C19SMN1; SMN2F2ALDH1A1
Sulfuric Acid SCHEMBL28531626 0.88 CYP2C19 (0.49) DPP4CYP2C19SMN1; SMN2F2ALDH1A1
SCHEMBL3466950 0.81 CYP2C19 (0.43) DPP4CYP2C19SMN1; SMN2ALDH1A1KDM4E
SCHEMBL14890157 0.78 CYP2C19 (0.40) DPP4CYP2C19SMN1; SMN2
Hydrochloric Acid SCHEMBL5624213 0.78 HTR2A (0.41) DPP4CYP2C19SMN1; SMN2ALDH1A1KDM4E
SCHEMBL898390 0.77 CYP2C19 (0.57) DPP4CYP2C19SMN1; SMN2F2ALDH1A1
SCHEMBL7406881 0.77 CYP2C19 (0.57) DPP4CYP2C19SMN1; SMN2F2ALDH1A1
SCHEMBL4629946 0.77 CYP2C19 (0.57) DPP4CYP2C19SMN1; SMN2F2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3354666-B1 USE OF AN POLYACRYLAMIDE RESIN AS PAPERMAKING ADDITIVE AND PAPER HARIMA CHEMICALS INC (JP) 2021-03-10 EP disclosed
CN-111826959-A Flame retardant auxiliary, flame retardant processing agent composition, and method for producing flame-retardant fiber fabric 日华化学株式会社 2020-10-27 CN disclosed
US-20200332131-A1 FLAME RETARDANT AID, FLAME RETARDING AGENT COMPOSITION, AND METHOD FOR PRODUCING FLAME-RETARDANT FIBER FABRIC NICCA CHEMICAL CO., LTD. (JP) 2020-10-22 US disclosed
EP-3354666-A1 POLYACRYLAMIDE RESIN, PAPERMAKING ADDITIVE AND PAPER Harima Chemicals, Inc. (JP) 2018-08-01 EP disclosed
US-9908959-B2 Polyacrylamide resin, papermaking additive, and paper HARIMA CHEMICALS, INCORPORATED (JP) 2018-03-06 US disclosed
US-20170253683-A1 POLYACRYLAMIDE RESIN, PAPERMAKING ADDITIVE, AND PAPER HARIMA CHEMICALS, INCORPORATED (JP) 2017-09-07 US disclosed
US-20150211130-A1 ANTI-CORROSIVE AGENT FOR WASHING OF METAL WITH ACID, DETERGENT SOLUTION COMPOSITION, AND METHOD FOR WASHING OF METAL NITTO BOSEKI CO LTD (JP) 2015-07-30 US disclosed
US-20130109607-A1 ANTI-CORROSIVE AGENT FOR WASHING OF METAL WITH ACID, DETERGENT SOLUTION COMPOSITION, AND METHOD FOR WASHING OF METAL NITTO BOSEKI CO., LTD. (JP) 2013-05-02 US disclosed
EP-2199265-B1 GLASS FIBER SIZING AGENT CONTAINING AMPHOTERIC POLYMER COMPOUND NITTO BOSEKI CO LTD (JP) 2012-11-07 EP disclosed
US-20100215940-A1 Glass Fiber Sizing Agent Containing Amphoteric Polymer Compound NITTO BOSEKI CO., LTD. (JP) 2010-08-26 US disclosed
EP-2199265-A1 GLASS FIBER SIZING AGENT CONTAINING AMPHOTERIC POLYMER COMPOUND Nitto Boseki CO., LTD. (JP) 2010-06-23 EP disclosed