Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 known ✓ | P27487 | 2/20 | 0.50 |
| ▸ | HTR2A known ✓ | P28223 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1678152 | 0.98 | DPP4 (0.52) | DPP4CYP2C19SMN1; SMN2ALDH1A1KDM4E | |
| Iodide SCHEMBL3466445 | 0.96 | DPP4 (0.50) | DPP4CYP2C19SMN1; SMN2ALDH1A1KDM4E | |
| Bromide SCHEMBL3466618 | 0.96 | DPP4 (0.50) | DPP4CYP2C19SMN1; SMN2ALDH1A1KDM4E | |
| Sulfuric Acid SCHEMBL28531626 | 0.88 | CYP2C19 (0.49) | DPP4CYP2C19SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL3466950 | 0.81 | CYP2C19 (0.43) | DPP4CYP2C19SMN1; SMN2ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL5624213 | 0.81 | HTR2A (0.41) | DPP4CYP2C19SMN1; SMN2ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL25188226 | 0.79 | CYP2C19 (0.55) | DPP4CYP2C19SMN1; SMN2ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL31471464 | 0.79 | CYP2C19 (0.55) | DPP4CYP2C19SMN1; SMN2ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL250191 | 0.79 | CYP2C19 (0.55) | DPP4CYP2C19SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL14890157 | 0.78 | CYP2C19 (0.40) | DPP4CYP2C19SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 381 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240191084-A1 | ANTIMICROBIAL AND ANTIVIRAL BUILDING PANELS | ARMSTRONG WORLD INDUSTRIES, INC. | 2024-06-13 | — | — | US | claimed |
| CN-117510692-A | High-salt-water gel vacuum bag with flame-retardant and heat-insulating functions and preparation method thereof | 中国人民解放军火箭军工程大学 | 2024-02-06 | — | — | CN | claimed |
| CN-115477729-A | Narrow molecular weight cationic polyacrylamide dry strength agent and preparation method thereof | 济宁明升新材料有限公司 | 2022-12-16 | — | — | CN | claimed |
| CN-109266058-B | Catalysis method and use method of water-based inorganic nano-coating | 湖南凯斯利新材料有限公司 | 2021-07-16 | — | — | CN | claimed |
| CN-109281166-B | Protein fiber antibacterial finishing method based on enzymatic graft copolymerization | 江南大学 | 2020-10-27 | — | — | CN | claimed |
| US-10563347-B2 | Antibacterial/antifungal finished product production method, and antibacterial/antifungal finished product produced by the method | OSAKA KASEI CO., LTD. (JP) | 2020-02-18 | — | — | US | claimed |
| US-8217080-B2 | Anti-infective methods and systems for treating pathogen-induced disordered tissues | CHURCH & DWIGHT CO., INC. | 2012-07-10 | — | — | US | claimed |
| US-20110245784-A1 | ANTI-INFECTIVE COMPOSITIONS, METHODS AND SYSTEMS FOR TREATING PATHOGEN-INDUCED DISORDERED TISSUES | QUADEX PHARMACEUTICALS, LLC (US) | 2011-10-06 | — | — | US | claimed |
| US-20100314485-A1 | Center-Pull Dispenser for Web Material | NATIONAL TISSUE COMPANY LLC | 2010-12-16 | — | — | US | claimed |
| EP-1404174-B1 | ANTI-INFECTIVE COMPOSITIONS FOR TREATING DISORDERED TISSUE SUCH AS COLD SORES | QUADEX PHARMACEUTICALS LLC (US) | 2010-12-15 | — | — | EP | claimed |
| EP-2046932-A2 | COMPOSITION FOR IMPROVING WETTABILITY OF SURFACES | Ciba Holding Inc. (CH) | 2009-04-15 | — | — | EP | claimed |
| US-20080033106-A1 | Composition for improving wettability of surfaces | CIBA SPECIALTY CHEMICALS CORP. | 2008-02-07 | — | — | US | claimed |
| WO-2008015138-A2 | COMPOSITION FOR IMPROVING WETTABILITY OF SURFACES | CIBA HOLDING INC. (CH) | 2008-02-07 | — | — | WO | claimed |
| EP-1881778-A1 | CENTER-PULL DISPENSER FOR WEB MATERIAL | Buckeye Technologies Inc. (US) | 2008-01-30 | — | — | EP | claimed |
| US-20060261076-A1 | Center-pull dispenser for web material | BKI HOLDING CORPORATION (US) | 2006-11-23 | — | — | US | claimed |
| WO-2006124429-A1 | CENTER-PULL DISPENSER FOR WEB MATERIAL | BUCKEYE TECHNOLOGIES INC. (US) | 2006-11-23 | — | — | WO | claimed |
| US-6423750-B1 | LIQUID CONTAINING PENETRATION ADJUVANT | CHURCH & DWIGHT CO., INC. | 2002-07-23 | — | — | US | claimed |
| US-6420431-B1 | TOPICALLY APPLYING QUATERNARY AMMONIUM COMPOUND (SUCH AS BENZALKONIUM CHLORIDE) TO COLD SORE AND RUBBING; COMPOUND PENETRATES SKIN WITHOUT DIFFUSION; QUICK RELIEF | CHURCH & DWIGHT CO., INC. | 2002-07-16 | — | — | US | claimed |
| US-6414032-B1 | CONTAINING PENETRATION INTENSIFIER AND ANTIINFECTIVE AGENTS; TOPICAL APPLYING | CHURCH & DWIGHT CO., INC. | 2002-07-02 | — | — | US | claimed |
| WO-1993021766-A1 | QUATERNARY AMMONIUM COMPOSITION AND PROCESS | ETHYL CORPORATION (US) | 1993-11-11 | — | — | WO | claimed |