⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1804491 | 0.85 | MAPK1 (0.36) | — | |
| SCHEMBL28829815 | 0.76 | MAPK1 (0.35) | — | |
| SCHEMBL8536801 | 0.69 | — | — | |
| SCHEMBL4007003 | 0.69 | — | — | |
| SCHEMBL17667432 | 0.68 | MAPK1 (0.40) | — | |
| SCHEMBL4300539 | 0.68 | — | — | |
| SCHEMBL27240613 | 0.68 | MAPK1 (0.40) | — | |
| SCHEMBL17495567 | 0.65 | MAPK1 (0.37) | — | |
| SCHEMBL16095938 | 0.64 | F2 (0.33) | — | |
| SCHEMBL7117715 | 0.62 | DRD2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2265600-A1 | PYRIDINYL AMIDES FOR THE TREATMENT OF CNS AND METABOLIC DISORDERS | Pfizer Inc. (US) | 2010-12-29 | — | — | EP | disclosed |
| WO-2009098576-A1 | PYRIDINYL AMIDES FOR THE TREATMENT OF CNS AND METABOLIC DISORDERS | PFIZER INC. (US) | 2009-08-13 | — | — | WO | disclosed |
| US-20090197859-A1 | Pyridinyl Amides for the Treatment of CNS and Metabolic Disorders | PFIZER INC. | 2009-08-06 | — | — | US | disclosed |