⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20142603 | 0.82 | SMN1; SMN2 (0.30) | — | |
| SCHEMBL21434936 | 0.80 | — | — | |
| SCHEMBL7117715 | 0.77 | DRD2 (0.31) | — | |
| SCHEMBL755868 | 0.70 | — | — | |
| SCHEMBL17438246 | 0.70 | — | — | |
| SCHEMBL3466735 | 0.69 | — | — | |
| SCHEMBL1804491 | 0.69 | MAPK1 (0.36) | — | |
| SCHEMBL1122435 | 0.65 | ALDH1A1 (0.32) | — | |
| SCHEMBL4395008 | 0.65 | — | — | |
| SCHEMBL19547248 | 0.65 | DYRK1A (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9000175-B2 | Bicyclic GPR119 modulators | LUPIN LIMITED (IN) | 2015-04-07 | — | — | US | disclosed |
| EP-2643311-A1 | BICYCLIC GPR119 MODULATORS | Lupin Limited (IN) | 2013-10-02 | — | — | EP | disclosed |
| US-20130245000-A1 | BICYCLIC GPR119 MODULATORS | LUPIN LIMITED (IN) | 2013-09-19 | — | — | US | disclosed |
| WO-2012069917-A1 | BICYCLIC GPR119 MODULATORS | LUPIN LIMITED (IN) | 2012-05-31 | — | — | WO | disclosed |