Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 4/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 5/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TACR2 | P21452 | 2/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7765696 | 0.92 | L3MBTL1 (0.35) | SLC6A4SLC6A3P2RX3SLC6A2L3MBTL1 | |
| SCHEMBL6950573 | 0.92 | TACR1 (0.39) | SLC6A4SLC6A3SLC6A2TACR1TACR2 | |
| SCHEMBL7766689 | 0.87 | SLC6A3 (0.39) | SLC6A4SLC6A3SLC6A2TACR1TACR2 | |
| SCHEMBL7764201 | 0.86 | TACR1 (0.40) | SLC6A4SLC6A3SLC6A2TACR1MEN1 | |
| SCHEMBL5203734 | 0.84 | MEN1 (0.34) | P2RX3L3MBTL1MEN1KMT2AKDM4C | |
| SCHEMBL7765670 | 0.82 | SLC6A3 (0.39) | SLC6A4SLC6A3SLC6A2TACR1MEN1 | |
| SCHEMBL6544366 | 0.82 | SLC6A3 (0.38) | SLC6A4SLC6A3SLC6A2TACR1MEN1 | |
| SCHEMBL7956526 | 0.77 | MEN1 (0.38) | SLC6A4SLC6A3SLC6A2TACR1MEN1 | |
| SCHEMBL4630125 | 0.77 | SLC6A3 (0.37) | SLC6A4SLC6A3SLC6A2TACR1MEN1 | |
| SCHEMBL6957304 | 0.76 | SLC6A2 (0.50) | SLC6A4SLC6A3SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010071575-A1 | QUATERNARY PIPERIDINE DERIVATIVES AND USES THEREOF | ASTRAZENECA AB (SE) | 2010-06-24 | — | — | WO | disclosed |
| WO-2010071575-A1 | QUATERNARY PIPERIDINE DERIVATIVES AND USES THEREOF | ASTRAZENECA AB (SE) | 2010-06-24 | — | — | WO | disclosed |