Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | GGT1 | P19440 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3467783 | 0.91 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL5390639 | 0.86 | ALDH1A1 (0.73) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL3466719 | 0.84 | SMN1; SMN2 (0.59) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL3467586 | 0.83 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL5393345 | 0.81 | ALDH1A1 (0.66) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL3468247 | 0.81 | ALDH1A1 (0.66) | ALDH1A1MEN1KMT2AMAPTHPGD | |
| SCHEMBL3467885 | 0.80 | ALDH1A1 (0.65) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL3467474 | 0.79 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL5391650 | 0.78 | POLB (0.75) | ALDH1A1MEN1KMT2AMAPTHPGD | |
| SCHEMBL3466755 | 0.78 | ALDH1A1 (0.62) | ALDH1A1MEN1KMT2AMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010073011-A2 | COMPOUNDS USEFUL AS MEDICAMENTS | BETAGENON AB (SE) | 2010-07-01 | — | — | WO | disclosed |