Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | HPGD | P15428 | 5/20 | 0.59 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | AR | P10275 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3466719 | 0.94 | SMN1; SMN2 (0.59) | ALDH1A1SMN1; SMN2MEN1KMT2AHPGD | |
| SCHEMBL3467566 | 0.87 | ALDH1A1 (0.66) | ALDH1A1SMN1; SMN2MEN1KMT2AHPGD | |
| SCHEMBL3467085 | 0.86 | SMN1; SMN2 (0.51) | ALDH1A1SMN1; SMN2MEN1KMT2AHPGD | |
| SCHEMBL3467586 | 0.83 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2MEN1KMT2AHPGD | |
| SCHEMBL3466980 | 0.79 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2MEN1KMT2AHPGD | |
| SCHEMBL3467153 | 0.79 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2MEN1KMT2AHPGD | |
| SCHEMBL3466833 | 0.77 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2MEN1KMT2AHPGD | |
| SCHEMBL5398285 | 0.77 | NPC1 (0.54) | ALDH1A1SMN1; SMN2MEN1KMT2AHPGD | |
| SCHEMBL3467041 | 0.76 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2MEN1KMT2AHPGD | |
| SCHEMBL3467295 | 0.76 | ALDH1A1 (0.81) | ALDH1A1SMN1; SMN2MEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010073011-A2 | COMPOUNDS USEFUL AS MEDICAMENTS | BETAGENON AB (SE) | 2010-07-01 | — | — | WO | claimed |
| WO-2010073011-A2 | COMPOUNDS USEFUL AS MEDICAMENTS | BETAGENON AB (SE) | 2010-07-01 | — | — | WO | disclosed |