Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 2/20 | 0.60 |
| ▸ | PGK1 | P00558 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.47 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.47 |
| ▸ | RPS6KB2 | Q9UBS0 | 2/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.46 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | G6PD | P11413 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11207512 | 0.88 | NQO2 (0.52) | NQO2PGK1ALDH1A1PDGFRBPDGFRA | |
| SCHEMBL11203601 | 0.84 | POLB (0.47) | NQO2PGK1ALDH1A1MAPTGAA | |
| SCHEMBL650718 | 0.84 | NQO2 (0.50) | NQO2PGK1ALDH1A1PDGFRBPDGFRA | |
| SCHEMBL11205485 | 0.84 | NQO2 (0.45) | NQO2PGK1ALDH1A1KDM4EGLA | |
| SCHEMBL29029328 | 0.81 | NQO2 (0.62) | NQO2PGK1ALDH1A1PDGFRBPDGFRA | |
| SCHEMBL11202172 | 0.81 | PDE4A (0.47) | NQO2PGK1ALDH1A1PDGFRBPDGFRA | |
| SCHEMBL11207779 | 0.81 | NQO2 (0.43) | NQO2PGK1ALDH1A1PDGFRBPDGFRA | |
| SCHEMBL11477391 | 0.80 | NQO2 (0.46) | NQO2PGK1ALDH1A1PDGFRBPDGFRA | |
| SCHEMBL11696562 | 0.78 | PDE4A (0.54) | NQO2PGK1ALDH1A1PDGFRBPDGFRA | |
| SCHEMBL31530749 | 0.77 | PGK1 (0.68) | NQO2PGK1ALDH1A1PDGFRBPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104854458-B | Methylglyoxal as a marker for cancer | 抗癌治疗研究协会 | 2018-02-09 | — | — | CN | claimed |
| EP-0014688-B1 | PROCESS FOR THE TREATMENT OF SILVER DYE-BLEACHING MATERIALS, AQUEOUS PREPARATION THEREFOR, CONCENTRATE AND PROCESS FOR MAKING THE PREPARATION | CIBA-GEIGY AG (CH) | 1983-03-23 | — | — | EP | claimed |
| US-4304846-A | USING MIXTURES OF A 1,4- OR 1,2-DIAZINE AS BLEACHING CATALYSTS; PREFERENTIAL REDOX POTENTIALS | CIBA-GEIGY AG (CH) | 1981-12-08 | — | — | US | claimed |
| EP-0014688-A2 | Process for the treatment of silver dye-bleaching materials, aqueous preparation therefor, concentrate and process for making the preparation | CIBA-GEIGY AG (CH) | 1980-08-20 | — | — | EP | claimed |
| EP-3301448-B1 | METHYLGLYOXAL AS A MARKER OF CANCER | ASSOCIATION POUR LA RECH THERAPEUTIQUE ANTI CANCEREUSE (FR) | 2021-03-03 | — | — | EP | disclosed |
| EP-3301448-A1 | METHYLGLYOXAL AS A MARKER OF CANCER | Association pour la Recherche Thérapeutique Anti-Cancéreuse (FR) | 2018-04-04 | — | — | EP | disclosed |
| CN-104854458-B | Methylglyoxal as a marker for cancer | 抗癌治疗研究协会 | 2018-02-09 | — | — | CN | disclosed |
| EP-2912465-B1 | METHYLGLYOXAL AS A MARKER OF CANCER | ASS POUR LA RECH THÉRAPEUTIQUE ANTI-CANCÉREUSE (FR) | 2017-10-25 | — | — | EP | disclosed |
| US-20160178637-A1 | DETECTION OF ALPHA, BETA-DICARBONYL COMPOUNDS WITH FLUOROGENIC PROBES | THE UNIVERSITY OF WARWICK (GB) | 2016-06-23 | — | — | US | disclosed |
| EP-3030904-A1 | DETECTION OF ALPHA, BETA-DICARBONYL COMPOUNDS WITH FLUOROGENIC PROBES | The University Of Warwick (GB) | 2016-06-15 | — | — | EP | disclosed |
| US-20150301056-A1 | METHYLGLYOXAL AS A MARKER OF CANCER | ASSOCIATION POUR LA RECHERCHE THERAPEUTIQUE ANTI-CANCEREUSE (FR) | 2015-10-22 | — | — | US | disclosed |
| EP-2912465-A1 | METHYLGLYOXAL AS A MARKER OF CANCER | Association pour la Recherche Thérapeutique Anti-Cancéreuse (FR) | 2015-09-02 | — | — | EP | disclosed |
| EP-1767560-A1 | METHOD FOR PRODUCING AROMATIC COMPOUND POLYMER | Sumitomo Chemical Company, Limited (JP) | 2007-03-28 | — | — | EP | disclosed |
| WO-2005051968-A1 | TREATMENT OF SUGAR SOLUTIONS | WIVENHOE TECHNOLOGY LTD (GB) | 2005-06-09 | — | — | WO | disclosed |
| EP-0014688-B1 | PROCESS FOR THE TREATMENT OF SILVER DYE-BLEACHING MATERIALS, AQUEOUS PREPARATION THEREFOR, CONCENTRATE AND PROCESS FOR MAKING THE PREPARATION | CIBA-GEIGY AG (CH) | 1983-03-23 | — | — | EP | disclosed |
| US-4304846-A | USING MIXTURES OF A 1,4- OR 1,2-DIAZINE AS BLEACHING CATALYSTS; PREFERENTIAL REDOX POTENTIALS | CIBA-GEIGY AG (CH) | 1981-12-08 | — | — | US | disclosed |
| EP-0014688-A2 | Process for the treatment of silver dye-bleaching materials, aqueous preparation therefor, concentrate and process for making the preparation | CIBA-GEIGY AG (CH) | 1980-08-20 | — | — | EP | disclosed |
| US-4043819-A | Photo-polymerizable material for the preparation of stable polymeric images and process for making them by photopolymerization in a matrix | CIBA-GEIGY AG (CH) | 1977-08-23 | — | — | US | disclosed |
| US-4001017-A | REDOX CATALYSTS, DIAZINES, ELECTRON DONORS | CIBA-GEIGY AG (CH) | 1977-01-04 | — | — | US | disclosed |
| US-3961957-A | ACID, WATER SOLUBLE IODIDE | CIBA-GEIGY AG (CH) | 1976-06-08 | — | — | US | disclosed |