SCHEMBL11202172

SCHEMBL11202172

COc1cc2nc(C)c(CO)nc2cc1OC

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE4A P27815 2/20 0.47
PDE4D Q08499 2/20 0.47
PDE4B Q07343 1/20 0.47
PDE4C Q08493 1/20 0.47
NQO2 P16083 1/20 0.47
PGK1 P00558 5/20 0.46
PDGFRB P09619 1/20 0.38
PDGFRA P16234 1/20 0.38
HTT P42858 1/20 0.38
ALDH1A1 P00352 3/20 0.38
RPS6KB2 Q9UBS0 1/20 0.38
PDE3B Q13370 1/20 0.38
PDE3A Q14432 1/20 0.38
SMN1; SMN2 Q16637 3/20 0.37
PDE10A Q9Y233 1/20 0.37
DPP4 P27487 1/20 0.37
MAPK1 P28482 1/20 0.37
KDM4E B2RXH2 1/20 0.37
SLC10A2 Q12908 1/20 0.37
GLA P06280 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11696562 0.92 PDE4A (0.54) PDE4APDE4DPDE4BPDE4CNQO2
SCHEMBL11477391 0.83 NQO2 (0.46) NQO2PGK1PDGFRBPDGFRAALDH1A1
SCHEMBL11209776 0.81 NQO2 (0.41) PDE4APDE4DPDE4BPDE4CNQO2
SCHEMBL346704 0.81 NQO2 (0.60) NQO2PGK1PDGFRBPDGFRAALDH1A1
SCHEMBL8644060 0.77 PDE4A (0.61) PDE4APDE4DPDE4BPDE4CNQO2
SCHEMBL650718 0.76 NQO2 (0.50) PDE4APDE4DNQO2PGK1PDGFRB
SCHEMBL9700631 0.74 NQO2 (0.52) PDE4APDE4DPDE4BPDE4CNQO2
SCHEMBL16424551 0.74 LMNA (0.51) NQO2HTTALDH1A1SMN1; SMN2PDE10A
SCHEMBL11204856 0.73 GAA (0.40) ALDH1A1RPS6KB2SMN1; SMN2PDE10AKDM4E
SCHEMBL11209899 0.73 ALDH1A1 (0.40) HTTALDH1A1RPS6KB2SMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0014688-B1 PROCESS FOR THE TREATMENT OF SILVER DYE-BLEACHING MATERIALS, AQUEOUS PREPARATION THEREFOR, CONCENTRATE AND PROCESS FOR MAKING THE PREPARATION CIBA-GEIGY AG (CH) 1983-03-23 EP claimed
US-4304846-A USING MIXTURES OF A 1,4- OR 1,2-DIAZINE AS BLEACHING CATALYSTS; PREFERENTIAL REDOX POTENTIALS CIBA-GEIGY AG (CH) 1981-12-08 US claimed
EP-0014688-A2 Process for the treatment of silver dye-bleaching materials, aqueous preparation therefor, concentrate and process for making the preparation CIBA-GEIGY AG (CH) 1980-08-20 EP claimed
EP-0014688-B1 PROCESS FOR THE TREATMENT OF SILVER DYE-BLEACHING MATERIALS, AQUEOUS PREPARATION THEREFOR, CONCENTRATE AND PROCESS FOR MAKING THE PREPARATION CIBA-GEIGY AG (CH) 1983-03-23 EP disclosed
US-4304846-A USING MIXTURES OF A 1,4- OR 1,2-DIAZINE AS BLEACHING CATALYSTS; PREFERENTIAL REDOX POTENTIALS CIBA-GEIGY AG (CH) 1981-12-08 US disclosed
EP-0014688-A2 Process for the treatment of silver dye-bleaching materials, aqueous preparation therefor, concentrate and process for making the preparation CIBA-GEIGY AG (CH) 1980-08-20 EP disclosed
US-4216320-A Quinoxaline bleach catalysts CIBA-GEIGY AG (CH) 1980-08-05 US disclosed
US-4145217-A DYE BLEACH CATALYST CIBA-GEIGY AG (CH) 1979-03-20 US disclosed