Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.48 |
| ▸ | CTSB | P07858 | 1/20 | 0.48 |
| ▸ | ELANE | P08246 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.46 |
| ▸ | SCN1A | P35498 | 1/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.46 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.46 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3468957 | 0.90 | MEN1 (0.55) | MEN1KMT2AALDH1A1PKMMAPT | |
| SCHEMBL3467266 | 0.88 | ALDH1A1 (0.62) | MEN1KMT2AALDH1A1PKMMAPT | |
| SCHEMBL3467511 | 0.87 | MEN1 (0.52) | MEN1KMT2AALDH1A1PKMMAPT | |
| SCHEMBL3466835 | 0.84 | ALDH1A1 (0.50) | MEN1KMT2AALDH1A1PKMMAPT | |
| SCHEMBL3467359 | 0.83 | ALDH1A1 (0.52) | MEN1KMT2AALDH1A1PKMMAPT | |
| SCHEMBL5395378 | 0.80 | AKT1 (0.65) | MEN1KMT2AALDH1A1PKMMAPT | |
| SCHEMBL3467586 | 0.80 | ALDH1A1 (0.56) | MEN1KMT2AALDH1A1PKMMAPT | |
| SCHEMBL3467041 | 0.80 | ALDH1A1 (0.48) | MEN1KMT2AALDH1A1PKMMAPT | |
| SCHEMBL3467284 | 0.80 | NPC1 (0.50) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL3467515 | 0.78 | RECQL (0.56) | MEN1KMT2AALDH1A1PKMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010073011-A2 | COMPOUNDS USEFUL AS MEDICAMENTS | BETAGENON AB (SE) | 2010-07-01 | — | — | WO | disclosed |