Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 8/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | GGT1 | P19440 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3466835 | 0.92 | ALDH1A1 (0.50) | ALDH1A1MAPTPKMMEN1KMT2A | |
| SCHEMBL3466833 | 0.89 | ALDH1A1 (0.54) | ALDH1A1MAPTPKMMEN1KMT2A | |
| SCHEMBL3467152 | 0.83 | MEN1 (0.53) | ALDH1A1MAPTPKMMEN1KMT2A | |
| SCHEMBL3467885 | 0.83 | ALDH1A1 (0.65) | ALDH1A1MAPTMEN1KMT2ACA1 | |
| SCHEMBL3467511 | 0.82 | MEN1 (0.52) | ALDH1A1MAPTPKMMEN1KMT2A | |
| SCHEMBL3467586 | 0.82 | ALDH1A1 (0.56) | ALDH1A1MAPTPKMMEN1KMT2A | |
| SCHEMBL3468245 | 0.81 | ALDH1A1 (0.52) | ALDH1A1MAPTPKMMEN1KMT2A | |
| SCHEMBL3467186 | 0.78 | ATM (0.52) | ALDH1A1PKMMEN1KMT2ACA1 | |
| SCHEMBL3468791 | 0.77 | ALDH1A1 (0.55) | ALDH1A1MAPTMEN1KMT2ACA1 | |
| SCHEMBL3466966 | 0.75 | SMN1; SMN2 (0.54) | ALDH1A1MAPTPKMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010073011-A2 | COMPOUNDS USEFUL AS MEDICAMENTS | BETAGENON AB (SE) | 2010-07-01 | — | — | WO | claimed |
| WO-2010073011-A2 | COMPOUNDS USEFUL AS MEDICAMENTS | BETAGENON AB (SE) | 2010-07-01 | — | — | WO | disclosed |