Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC20 | Q5W0Z9 | 3/20 | 0.77 |
| ▸ | ZDHHC2 | Q9UIJ5 | 2/20 | 0.77 |
| ▸ | EPHX1 | P07099 | 8/20 | 0.47 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.44 |
| ▸ | CASP2 | P42575 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | THRA | P10827 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.41 |
| ▸ | TGM2 | P21980 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3467554 | 1.00 | ZDHHC20 (0.77) | ZDHHC20ZDHHC2EPHX1PLA2G2ACASP2 | |
| Methacrylic Acid SCHEMBL1813078 | 0.89 | ZDHHC2 (0.80) | ZDHHC20ZDHHC2EPHX1PLA2G2ACASP2 | |
| Methacrylic Acid SCHEMBL19461112 | 0.89 | ZDHHC2 (0.80) | ZDHHC20ZDHHC2EPHX1PLA2G2ACASP2 | |
| SCHEMBL10386869 | 0.88 | ZDHHC20 (0.56) | ZDHHC20ZDHHC2TGM2 | |
| SCHEMBL3467775 | 0.88 | ZDHHC20 (0.60) | ZDHHC20ZDHHC2EPHX1PLA2G2ACASP2 | |
| SCHEMBL144546 | 0.88 | EPHX1 (0.59) | ZDHHC20ZDHHC2EPHX1PLA2G2ACASP2 | |
| SCHEMBL146327 | 0.88 | EPHX1 (0.59) | ZDHHC20ZDHHC2EPHX1PLA2G2ACASP2 | |
| SCHEMBL149423 | 0.88 | EPHX1 (0.59) | ZDHHC20ZDHHC2EPHX1PLA2G2ACASP2 | |
| SCHEMBL220516 | 0.88 | ZDHHC20 (1.00) | ZDHHC20ZDHHC2EPHX1CASP2EGFR | |
| SCHEMBL346798 | 0.88 | ZDHHC20 (1.00) | ZDHHC20ZDHHC2EPHX1CASP2EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010069514-A1 | RELATIVE PERMEABILITY MODIFIERS BASED ON HYDROPHOBICALLY MODIFIED CATIONIC COPOLYMERS | ENI S.P.A. (IT) | 2010-06-24 | — | — | WO | disclosed |