SCHEMBL346798

SCHEMBL346798

C=CC(=O)NCCCCCCCCCCC

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ZDHHC20 Q5W0Z9 3/20 1.00
ZDHHC2 Q9UIJ5 3/20 1.00
EPHX1 P07099 9/20 0.59
CASP2 P42575 1/20 0.53
EGFR P00533 1/20 0.50
NAAA Q02083 1/20 0.50
ALDH1A1 P00352 1/20 0.48
TSHR P16473 1/20 0.48
MAPK1 P28482 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
FAAH O00519 1/20 0.47
TGM2 P21980 1/20 0.46
THRA P10827 1/20 0.46
THRB P10828 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16193831 1.00 ZDHHC20 (1.00) ZDHHC20ZDHHC2EPHX1CASP2EGFR
SCHEMBL220516 1.00 ZDHHC20 (1.00) ZDHHC20ZDHHC2EPHX1CASP2EGFR
SCHEMBL14857206 1.00 ZDHHC20 (1.00) ZDHHC20ZDHHC2EPHX1CASP2EGFR
SCHEMBL890059 1.00 ZDHHC20 (1.00) ZDHHC20ZDHHC2EPHX1CASP2EGFR
SCHEMBL25793 1.00 ZDHHC20 (1.00) ZDHHC20ZDHHC2EPHX1CASP2EGFR
SCHEMBL17183678 1.00 ZDHHC20 (1.00) ZDHHC20ZDHHC2EPHX1CASP2EGFR
SCHEMBL10820746 1.00 ZDHHC20 (1.00) ZDHHC20ZDHHC2EPHX1CASP2EGFR
SCHEMBL426782 1.00 ZDHHC20 (1.00) ZDHHC20ZDHHC2EPHX1CASP2EGFR
SCHEMBL8087553 1.00 ZDHHC20 (1.00) ZDHHC20ZDHHC2EPHX1CASP2EGFR
SCHEMBL719563 1.00 ZDHHC20 (1.00) ZDHHC20ZDHHC2EPHX1CASP2EGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 821 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114324320-B Efficient and recyclable pH test paper and preparation method thereof 浙江正信石油科技有限公司 2024-08-13 CN claimed
CN-113563510-B Temperature-resistant salt-resistant comb polymer fluid loss additive for drilling mud bentonite 建平天正矿业有限公司 2022-09-06 CN claimed
CN-114324320-A Efficient and recyclable pH test paper and preparation method thereof 浙江正信石油科技有限公司 2022-04-12 CN claimed
CN-113563510-A Temperature-resistant salt-resistant comb polymer fluid loss additive for drilling mud bentonite 建平天正矿业有限公司 2021-10-29 CN claimed
US-20120027698-A9 COSMETIC AND/OR PHARMACEUTICAL COMPOSITION COMPRISING AT LEAST ONE COPOLYMER COMPRISING AT LEAST ONE IONIZABLE GROUP, AND COSMETIC TREATMENT PROCESS L'OREAL S.A. 2012-02-02 US claimed
US-20100278764-A1 COSMETIC AND/OR PHARMACEUTICAL COMPOSITION COMPRISING AT LEAST ONE COPOLYMER COMPRISING AT LEAST ONE IONIZABLE GROUP, AND COSMETIC TREATMENT PROCESS L'OREAL S.A. 2010-11-04 US claimed
EP-1514884-B1 Block copolymer comprising a vinyllactam block, cosmetic composition and use of this polymer in cosmetics OREAL (FR) 2009-08-26 EP claimed
US-7351405-B2 Long-lasting cosmetic composition for application to human hair, such as eyelashes and eyebrows L'OREAL (FR) 2008-04-01 US claimed
EP-1870075-A1 Mascara comprising at least 21% of wax and a filler L'Oréal (FR) 2007-12-26 EP claimed
US-20070264208-A1 Cosmetic and/or pharmaceutical composition comprising at least one copolymer comprising at least one ionizable group, and cosmetic treatment process L'OREAL S.A. (FR) 2007-11-15 US claimed
EP-1510533-B1 Block copolymer comprising a vinylactam block, cosmetic composition and use of this polymer in cosmetics OREAL (FR) 2006-12-06 EP claimed
EP-1249225-B1 Mascara containing an acrylic polymer OREAL (FR) 2006-10-11 EP claimed
US-20060088487-A1 Block ethylenic copolymers comprising a vinyllactam block, cosmetic or pharmaceutical compositions containing them and cosmetic use of these copolymers L'OREAL S.A. (FR) 2006-04-27 US claimed
US-20050238594-A1 Block ethylenic copolymers comprising a vinyllactam block, cosmetic or pharmaceutical compositions comprising them and cosmetic use of these copolymers L'OREAL S.A. (FR) 2005-10-27 US claimed
US-20050101740-A1 Block ethylenic copolymers comprising a vinyllactam block, cosmetic compositions containing them and cosmetic use of these copolymers L'OREAL S.A. (FR) 2005-05-12 US claimed
US-20020187116-A1 Long-lasting cosmetic composition for application to human hair, such as eyelashes and eyebrows L'OREAL (FR) 2002-12-12 US claimed
EP-1249225-A1 Mascara containing an acrylic polymer L'OREAL (FR) 2002-10-16 EP claimed
EP-4547208-B1 PROCESS FOR REMOVING THE COLOUR FROM PREVIOUSLY DYED KERATINOUS HAIR FIBRES OREAL (FR) 2026-05-27 EP disclosed
WO-1996037525-A1 WATER-SOLUBLE COPOLYMERS CONTAINING POLYMERIZED-IN CROSS-LINKING AGENTS, PROCESS FOR THEIR PREPARATION AND THEIR USE BASF AKTIENGESELLSCHAFT (DE) 1996-11-28 WO disclosed
EP-0687694-A2 Process for producing polymerizates based on 1-vinylimidazoles BASF AKTIENGESELLSCHAFT (DE) 1995-12-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050238594-A1 Block ethylenic copolymers comprising a vinyllactam block, cosmetic or pharmaceutical compositions comprising them and cosmetic use of these copolymers KRT18, DSG1, VCL ZDHHC20 4616/4885ZDHHC2 4780/4885EPHX1 26/4885
US-20060088487-A1 Block ethylenic copolymers comprising a vinyllactam block, cosmetic or pharmaceutical compositions containing them and cosmetic use of these copolymers KRT18, CUTA, SCNN1B ZDHHC20 3561/4885ZDHHC2 3876/4885EPHX1 628/4885
US-20070264208-A1 Cosmetic and/or pharmaceutical composition comprising at least one copolymer comprising at least one ionizable group, and cosmetic treatment process KRT18, DSG1, DSC1 ZDHHC20 1386/4885ZDHHC2 2918/4885EPHX1 1218/4885
US-20120027698-A9 COSMETIC AND/OR PHARMACEUTICAL COMPOSITION COMPRISING AT LEAST ONE COPOLYMER COMPRISING AT LEAST ONE IONIZABLE GROUP, AND COSMETIC TREATMENT PROCESS KRT18, DSG1, DSC1 ZDHHC20 1354/4885ZDHHC2 2971/4885EPHX1 1094/4885
US-20100278764-A1 COSMETIC AND/OR PHARMACEUTICAL COMPOSITION COMPRISING AT LEAST ONE COPOLYMER COMPRISING AT LEAST ONE IONIZABLE GROUP, AND COSMETIC TREATMENT PROCESS KRT18, DSG1, DSC1 ZDHHC20 1354/4885ZDHHC2 2971/4885EPHX1 1094/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.