Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SCD | O00767 | 1/20 | 0.43 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.40 |
| ▸ | GGT1 | P19440 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.39 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.38 |
| ▸ | CCR2 | P41597 | 1/20 | 0.38 |
| ▸ | GLS | O94925 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3467605 | 0.87 | ALDH1A1 (0.57) | ALDH1A1HSD17B10HPGDLMNASCD | |
| SCHEMBL3467368 | 0.83 | ALDH1A1 (0.46) | ALDH1A1HSD17B10HPGDLMNASCD | |
| SCHEMBL3467499 | 0.82 | ALDH1A1 (0.58) | ALDH1A1HSD17B10HPGDLMNASCD | |
| SCHEMBL3467458 | 0.80 | ALDH1A1 (0.61) | ALDH1A1HSD17B10HPGDLMNAGGT1 | |
| SCHEMBL3467235 | 0.78 | ALDH1A1 (0.49) | ALDH1A1HSD17B10HPGDLMNASCD | |
| SCHEMBL3467123 | 0.77 | MEN1 (0.47) | ALDH1A1HSD17B10HPGDLMNASCD | |
| SCHEMBL3467612 | 0.77 | MEN1 (0.67) | ALDH1A1HSD17B10HPGDSCDGGT1 | |
| SCHEMBL3467259 | 0.76 | KMT2A (0.55) | ALDH1A1HSD17B10LMNASCDGGT1 | |
| SCHEMBL3466859 | 0.76 | MEN1 (0.65) | ALDH1A1SCDGGT1MEN1KMT2A | |
| SCHEMBL3467243 | 0.74 | P2RY1 (0.52) | ALDH1A1HSD17B10SCDGGT1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010073011-A2 | COMPOUNDS USEFUL AS MEDICAMENTS | BETAGENON AB (SE) | 2010-07-01 | — | — | WO | claimed |
| WO-2010073011-A2 | COMPOUNDS USEFUL AS MEDICAMENTS | BETAGENON AB (SE) | 2010-07-01 | — | — | WO | disclosed |