Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.43 |
| ▸ | CCND1 | P24385 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | CDK7 | P50613 | 1/20 | 0.43 |
| ▸ | CCNH | P51946 | 1/20 | 0.43 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.43 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | SCD | O00767 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3467458 | 0.87 | ALDH1A1 (0.61) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL3467235 | 0.83 | ALDH1A1 (0.49) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL3467283 | 0.83 | ALDH1A1 (0.44) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL3466995 | 0.81 | ALDH1A1 (0.51) | ALDH1A1MAPTHSD11B1MEN1KMT2A | |
| SCHEMBL3467499 | 0.81 | ALDH1A1 (0.58) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL3467605 | 0.80 | ALDH1A1 (0.57) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL3468790 | 0.78 | ALDH1A1 (0.49) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL3467953 | 0.77 | ALDH1A1 (0.51) | ALDH1A1MAPTHSD11B1MEN1KMT2A | |
| SCHEMBL3467612 | 0.77 | MEN1 (0.67) | ALDH1A1MAPTMEN1KMT2AHSD17B10 | |
| SCHEMBL3467123 | 0.77 | MEN1 (0.47) | ALDH1A1MAPTMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010073011-A2 | COMPOUNDS USEFUL AS MEDICAMENTS | BETAGENON AB (SE) | 2010-07-01 | — | — | WO | claimed |
| WO-2010073011-A2 | COMPOUNDS USEFUL AS MEDICAMENTS | BETAGENON AB (SE) | 2010-07-01 | — | — | WO | disclosed |