Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3467511 | 0.90 | MEN1 (0.52) | KMT2AMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL3468957 | 0.86 | MEN1 (0.55) | KMT2AMEN1ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL3467276 | 0.85 | ALDH1A1 (0.58) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL3467566 | 0.82 | ALDH1A1 (0.66) | KMT2AMEN1ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL3468245 | 0.82 | ALDH1A1 (0.52) | KMT2AMEN1ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL3466833 | 0.82 | ALDH1A1 (0.54) | KMT2AMEN1ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL3467085 | 0.79 | SMN1; SMN2 (0.51) | KMT2AMEN1ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL3467984 | 0.79 | ALDH1A1 (0.52) | KMT2AMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL3466719 | 0.78 | SMN1; SMN2 (0.59) | KMT2AMEN1ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL3467284 | 0.76 | NPC1 (0.50) | KMT2AMEN1ALDH1A1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010073011-A2 | COMPOUNDS USEFUL AS MEDICAMENTS | BETAGENON AB (SE) | 2010-07-01 | — | — | WO | claimed |
| WO-2010073011-A2 | COMPOUNDS USEFUL AS MEDICAMENTS | BETAGENON AB (SE) | 2010-07-01 | — | — | WO | disclosed |