Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | HPGD | P15428 | 6/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3466719 | 0.91 | SMN1; SMN2 (0.59) | SMN1; SMN2NPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL3467041 | 0.91 | ALDH1A1 (0.48) | SMN1; SMN2NPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL3467783 | 0.87 | ALDH1A1 (0.55) | SMN1; SMN2ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL3467474 | 0.86 | ALDH1A1 (0.62) | SMN1; SMN2NPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL3467586 | 0.81 | ALDH1A1 (0.56) | SMN1; SMN2NPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL3467863 | 0.80 | ALDH1A1 (0.45) | SMN1; SMN2ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL3467289 | 0.79 | KMT2A (0.54) | SMN1; SMN2NPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL3468957 | 0.78 | MEN1 (0.55) | SMN1; SMN2NPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL3466980 | 0.77 | ALDH1A1 (0.65) | SMN1; SMN2ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL3467566 | 0.76 | ALDH1A1 (0.66) | SMN1; SMN2NPC1RAB9AALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010073011-A2 | COMPOUNDS USEFUL AS MEDICAMENTS | BETAGENON AB (SE) | 2010-07-01 | — | — | WO | claimed |
| WO-2010073011-A2 | COMPOUNDS USEFUL AS MEDICAMENTS | BETAGENON AB (SE) | 2010-07-01 | — | — | WO | disclosed |