Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOX | P28300 | 1/20 | 0.46 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
| ▸ | CCR8 | P51685 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.38 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5700299 | 0.85 | SMN1; SMN2 (0.50) | LOXLOXL2S1PR1LMNASMN1; SMN2 | |
| SCHEMBL25272109 | 0.83 | LOX (0.44) | LOXLOXL2S1PR1LMNASMN1; SMN2 | |
| SCHEMBL30232338 | 0.83 | S1PR1 (0.53) | LOXLOXL2S1PR1LMNASMN1; SMN2 | |
| SCHEMBL29774730 | 0.77 | ALDH1A1 (0.43) | LMNASMN1; SMN2CCR1CCR5CCR8 | |
| SCHEMBL1072803 | 0.77 | ALDH1A1 (0.43) | LMNASMN1; SMN2CCR1CCR5CCR8 | |
| SCHEMBL3466579 | 0.76 | UHRF1 (0.46) | LMNASMN1; SMN2CCR1CCR5CCR8 | |
| SCHEMBL28157668 | 0.76 | ALDH1A1 (0.39) | LMNASMN1; SMN2ALDH1A1KDM4ETDP1 | |
| SCHEMBL16361065 | 0.76 | CCR1 (0.63) | LMNASMN1; SMN2CCR1CCR5CCR8 | |
| SCHEMBL8847160 | 0.74 | ALDH1A1 (0.41) | LMNASMN1; SMN2CCR1CCR5CCR8 | |
| SCHEMBL3468025 | 0.73 | SMN1; SMN2 (0.37) | LMNASMN1; SMN2ALDH1A1KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010085968-A1 | TOLUIDINE SULFONAMIDES AND THEIR USE AS HIF-INHIBITORS | EUROPEAN MOLECULAR BIOLOGY LABORATORY (EMBL) (DE) | 2010-08-05 | — | — | WO | disclosed |
| WO-2010076034-A1 | TOLUIDINE SULFONAMIDES AND THEIR USE AS-INHIBITORS | EUROPEAN MOLECULAR BIOLOGY LABORATORY (EMBL) (DE) | 2010-07-08 | — | — | WO | disclosed |
| CN-100358901-C | Cross-linked glycopeptide-cephalosporin antibiotics | THERAVANCE INC (US) | 2008-01-02 | — | — | CN | disclosed |
| CN-1329397-C | Cross-linked glycopeptide-cephalosporin antibiotics | THERAVANCE PHARMACY (US) | 2007-08-01 | — | — | CN | disclosed |
| CN-1781916-A | Cross-linked glycopeptide-cephalosporin antibiotics | THERAVANCE INC (US) | 2006-06-07 | — | — | CN | disclosed |
| CN-1568325-A | Cross-linked glycopeptide-cephalosporin antibiotics | THERAVANCE (US) | 2005-01-19 | — | — | CN | disclosed |