Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | NT5E | P21589 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.33 |
| ▸ | TUBB | P07437 | 2/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.33 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.33 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25215866 | 0.81 | LMNA (0.37) | SMN1; SMN2LMNAGABRG2GABRB3GABRA5 | |
| SCHEMBL3467323 | 0.73 | LOX (0.46) | SMN1; SMN2LMNATSHRTDP1ALDH1A1 | |
| SCHEMBL3468052 | 0.69 | NAMPT (0.43) | NAPRTAPLNR | |
| SCHEMBL2120289 | 0.69 | KDM4E (0.53) | SMN1; SMN2ALDH1A1MAPTNAPRTKCNH2 | |
| SCHEMBL9372292 | 0.69 | — | — | |
| SCHEMBL23151972 | 0.68 | ALDH1A1 (0.39) | SMN1; SMN2LMNAGABRG2GABRB3GABRA5 | |
| Hydrochloric Acid SCHEMBL27866010 | 0.68 | KDM4E (0.52) | SMN1; SMN2ALDH1A1MAPTKCNH2KDM4E | |
| Hydrochloric Acid SCHEMBL27809965 | 0.68 | NAMPT (0.42) | NAPRTAPLNR | |
| Hydrochloric Acid SCHEMBL28016002 | 0.68 | KDM4E (0.52) | SMN1; SMN2ALDH1A1MAPTKCNH2KDM4E | |
| SCHEMBL20338425 | 0.67 | KDM4E (0.50) | LMNATDP1ALDH1A1KDM4ECA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010085968-A1 | TOLUIDINE SULFONAMIDES AND THEIR USE AS HIF-INHIBITORS | EUROPEAN MOLECULAR BIOLOGY LABORATORY (EMBL) (DE) | 2010-08-05 | — | — | WO | disclosed |
| WO-2010076034-A1 | TOLUIDINE SULFONAMIDES AND THEIR USE AS-INHIBITORS | EUROPEAN MOLECULAR BIOLOGY LABORATORY (EMBL) (DE) | 2010-07-08 | — | — | WO | disclosed |
| US-4661340-A | Quail egg based stabilized foam compositions for cosmetic purposes | INTERKEMIA VEGYIPARI GAZDASAGI TARSASAG (HU) | 1987-04-28 | — | — | US | disclosed |