Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.51 |
| ▸ | NPC1 | O15118 | 6/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 2/20 | 0.42 |
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | GSK3A | P49840 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3467339 | 1.00 | RAB9A (0.51) | RAB9ASMN1; SMN2NPC1LMNAGAA | |
| SCHEMBL3467611 | 0.85 | NPC1 (0.60) | RAB9ASMN1; SMN2NPC1LMNAGAA | |
| SCHEMBL3467469 | 0.85 | RAB9A (0.51) | RAB9ASMN1; SMN2NPC1LMNAGAA | |
| SCHEMBL30677376 | 0.85 | NPC1 (0.51) | RAB9ASMN1; SMN2NPC1LMNAGAA | |
| SCHEMBL3467476 | 0.85 | RAB9A (0.51) | RAB9ASMN1; SMN2NPC1LMNAGAA | |
| SCHEMBL3467604 | 0.85 | NPC1 (0.60) | RAB9ASMN1; SMN2NPC1LMNAGAA | |
| SCHEMBL3467761 | 0.84 | RAB9A (0.56) | RAB9ASMN1; SMN2NPC1LMNAGAA | |
| SCHEMBL3467763 | 0.84 | RAB9A (0.56) | RAB9ASMN1; SMN2NPC1LMNAGAA | |
| SCHEMBL3466886 | 0.82 | RAB9A (0.51) | RAB9ASMN1; SMN2NPC1LMNAGAA | |
| SCHEMBL3467404 | 0.82 | RAB9A (0.48) | RAB9ASMN1; SMN2NPC1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010074746-A1 | METHODS OF USE FOR OPSIN BINDING LIGANDS | BIKAM PHARMACEUTICALS, INC. (US) | 2010-07-01 | — | — | WO | disclosed |
| WO-2010074746-A1 | METHODS OF USE FOR OPSIN BINDING LIGANDS | BIKAM PHARMACEUTICALS, INC. (US) | 2010-07-01 | — | — | WO | disclosed |