Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 9/20 | 0.60 |
| ▸ | RAB9A | P51151 | 8/20 | 0.60 |
| ▸ | MAPT | P10636 | 7/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.60 |
| ▸ | MEN1 | O00255 | 5/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CDC7 | O00311 | 1/20 | 0.43 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3467611 | 1.00 | NPC1 (0.60) | NPC1RAB9AMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL3467332 | 0.85 | RAB9A (0.51) | NPC1RAB9AMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL30677376 | 0.85 | NPC1 (0.51) | NPC1RAB9AMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL3467339 | 0.85 | RAB9A (0.51) | NPC1RAB9AMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL3467469 | 0.85 | RAB9A (0.51) | NPC1RAB9AMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL3467476 | 0.85 | RAB9A (0.51) | NPC1RAB9AMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL3467058 | 0.85 | NPC1 (0.67) | NPC1RAB9AMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL3467060 | 0.85 | NPC1 (0.67) | NPC1RAB9AMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL3467763 | 0.84 | RAB9A (0.56) | NPC1RAB9AMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL3467761 | 0.84 | RAB9A (0.56) | NPC1RAB9AMAPTKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010074746-A1 | METHODS OF USE FOR OPSIN BINDING LIGANDS | BIKAM PHARMACEUTICALS, INC. (US) | 2010-07-01 | — | — | WO | disclosed |
| WO-2010074746-A1 | METHODS OF USE FOR OPSIN BINDING LIGANDS | BIKAM PHARMACEUTICALS, INC. (US) | 2010-07-01 | — | — | WO | disclosed |