Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 14/20 | 0.70 |
| ▸ | NPC1 | O15118 | 12/20 | 0.70 |
| ▸ | AR | P10275 | 2/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.70 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.70 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.70 |
| ▸ | MEN1 | O00255 | 4/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.66 |
| ▸ | MAPT | P10636 | 5/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.66 |
| ▸ | TP53 | P04637 | 3/20 | 0.66 |
| ▸ | PKM | P14618 | 3/20 | 0.66 |
| ▸ | HPGD | P15428 | 3/20 | 0.66 |
| ▸ | GMNN | O75496 | 1/20 | 0.66 |
| ▸ | THPO | P40225 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Phenylquinoline SCHEMBL29399739 | 0.98 | RAB9A (0.73) | RAB9ANPC1ARCYP3A4CYP1A2 | |
| 2-Phenylquinoline SCHEMBL44999 | 0.98 | RAB9A (0.73) | RAB9ANPC1ARCYP3A4CYP1A2 | |
| 2-Phenylquinoline SCHEMBL29498037 | 0.95 | RAB9A (0.70) | RAB9ANPC1ARCYP3A4CYP1A2 | |
| 2-Phenylquinoline SCHEMBL29986142 | 0.95 | RAB9A (0.70) | RAB9ANPC1ARCYP3A4CYP1A2 | |
| 2-Phenylquinoline SCHEMBL668531 | 0.95 | RAB9A (0.70) | RAB9ANPC1ARCYP3A4CYP1A2 | |
| 2-Phenylquinoline SCHEMBL1815021 | 0.95 | RAB9A (0.70) | RAB9ANPC1ARCYP3A4CYP1A2 | |
| 2-Phenylquinoline SCHEMBL5733254 | 0.95 | RAB9A (0.70) | RAB9ANPC1ARCYP3A4CYP1A2 | |
| 2-Phenylquinoline SCHEMBL6858671 | 0.95 | RAB9A (0.70) | RAB9ANPC1ARCYP3A4CYP1A2 | |
| 2-Phenylquinoline SCHEMBL28871326 | 0.95 | RAB9A (0.70) | RAB9ANPC1ARCYP3A4CYP1A2 | |
| 2-Phenylquinoline SCHEMBL28983 | 0.95 | RAB9A (0.70) | RAB9ANPC1ARCYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10968229-B2 | Seven-membered ring compounds | IDEMITSU KOSAN CO., LTD. (JP) | 2021-04-06 | — | — | US | disclosed |
| US-10584126-B2 | 1-functionalized dibenzofurans and dibenzothiophenes for organic light emitting diodes (OLEDs) | IDEMITSU KOSAN CO., LTD. (JP) | 2020-03-10 | — | — | US | disclosed |
| US-20190119291-A1 | SEVEN-MEMBERED RING COMPOUNDS | IDEMITSU KOSAN CO., LTD. (JP) | 2019-04-25 | — | — | US | disclosed |
| US-20170362241-A1 | 1-FUNCTIONALIZED DIBENZOFURANS AND DIBENZOTHIOPHENES FOR ORGANIC LIGHT EMITTING DIODES (OLEDS) | IDEMITSU KOSAN CO., LTD. (JP) | 2017-12-21 | — | — | US | disclosed |
| US-9458182-B2 | Silyl- and heteroatom-substituted compounds selected from carbazoles, dibenzofurans, dibenzothiophenes and dibenzophospholes, and use thereof in organic electronics | BASF SE (DE) | 2016-10-04 | — | — | US | disclosed |
| US-20120012821-A1 | SILYL- AND HETEROATOM-SUBSTITUTED COMPOUNDS SELECTED FROM CARBAZOLES, DIBENZOFURANS, DIBENZOTHIOPHENES AND DIBENZOPHOSPHOLES, AND USE THEREOF IN ORGANIC ELECTRONICS | BASF SE (DE) | 2012-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190119291-A1 | SEVEN-MEMBERED RING COMPOUNDS | MCM7, XPO7, LUC7L2 | RAB9A 100/4885NPC1 923/4885AR 3285/4885 |
| US-10584126-B2 | 1-functionalized dibenzofurans and dibenzothiophenes for organic light emitting diodes (OLEDs) | OCIAD1, OCIAD2, DDT | RAB9A 2312/4885NPC1 817/4885AR 4486/4885 |
| US-10968229-B2 | Seven-membered ring compounds | MCM7, XPO7, LUC7L2 | RAB9A 100/4885NPC1 923/4885AR 3285/4885 |
| US-20120012821-A1 | SILYL- AND HETEROATOM-SUBSTITUTED COMPOUNDS SELECTED FROM CARBAZOLES, DIBENZOFURANS, DIBENZOTHIOPHENES AND DIBENZOPHOSPHOLES, AND USE THEREOF IN ORGANIC ELECTRONICS | DDT, CDKL1, CDK2 | RAB9A 3555/4885NPC1 4516/4885AR 4318/4885 |
| US-20170362241-A1 | 1-FUNCTIONALIZED DIBENZOFURANS AND DIBENZOTHIOPHENES FOR ORGANIC LIGHT EMITTING DIODES (OLEDS) | OCIAD1, OCIAD2, DDT | RAB9A 2312/4885NPC1 817/4885AR 4486/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.